Evidence map›Paper›PMID 36768598›Full record

ArticleInternational journal of molecular sciences2023

Immunohistochemical Expression Analysis of Caldesmon Isoforms in Colorectal Carcinoma Reveals Interesting Correlations with Tumor Characteristics.

Alya R Alnuaimi, Justus Bottner, Vidhya A Nair, Nival Ali, Razaz Alnakhli, Eva Dreyer, Iman M Talaat, Hauke Busch, Sven Perner, Jutta Kirfel and 2 more

Abstract read
In one paragraph

Article in International journal of molecular sciences, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed.

  1. Article
  2. A Prognostic Activity of Glutaredoxin 1 Protein (Grx1) in Colon Cancer.International journal of molecular sciences · 2024
    Article
  3. Article
  4. Article
  5. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors.

Alya R AlnuaimiSharjah Institute for Medical Research, University of Sharjah, Sharjah 27272, United Arab Emirates.
Justus BottnerInstitute of Pathology, University Hospital Schleswig-Holstein, 23560 Luebeck, Germany.
Vidhya A NairSharjah Institute for Medical Research, University of Sharjah, Sharjah 27272, United Arab Emirates.ORCID 0000-0002-5407-0130
Nival AliSharjah Institute for Medical Research, University of Sharjah, Sharjah 27272, United Arab Emirates.
Razaz AlnakhliSharjah Institute for Medical Research, University of Sharjah, Sharjah 27272, United Arab Emirates.
Eva DreyerInstitute of Pathology, University Hospital Schleswig-Holstein, 23560 Luebeck, Germany.
Iman M TalaatSharjah Institute for Medical Research, University of Sharjah, Sharjah 27272, United Arab Emirates.ORCID 0000-0002-5259-327X
Hauke BuschCollege of Medicine, University of Sharjah, Sharjah 27272, United Arab Emirates.ORCID 0000-0003-4763-4521
Sven PernerInstitute of Pathology, University Hospital Schleswig-Holstein, 23560 Luebeck, Germany.
Jutta KirfelInstitute of Pathology, University Hospital Schleswig-Holstein, 23560 Luebeck, Germany.
Rifat HamoudiSharjah Institute for Medical Research, University of Sharjah, Sharjah 27272, United Arab Emirates.ORCID 0000-0002-1402-0868
Wael M Abdel-RahmanSharjah Institute for Medical Research, University of Sharjah, Sharjah 27272, United Arab Emirates.ORCID 0000-0002-2149-1043

Funding

University of Sharjah 2001050155University of Sharjah College of Graduate Studies' grant to A.R.A.
6 · The paper itself

Abstract

Colorectal cancer is a notorious disease, with almost half of the patients succumbing to the disease. The prevalence and incidence rates of colorectal cancer are increasing in many parts of the world, highlighting the need to discover new biomarkers for diagnosis and therapy. Caldesmon (CaD), an actin-binding protein that plays a significant role in controlling cell motility, has emerged as a promising biomarker. The

Indexed as

Calmodulin-Binding ProteinsColorectal NeoplasmsBiomarkers, TumorCell MovementEpithelial CellsHumansProtein IsoformsTumor MicroenvironmentBiomarkers, TumorCalmodulin-Binding ProteinsProtein IsoformsCALD1caldesmonchemotherapycolorectal cancerinvasionl-CaDmetastasis

Identifiers

PMID36768598
PMCPMC9916900

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.