Evidence map›Paper›PMID 36768571›Full record

ArticleInternational journal of molecular sciences2023

Creation of a Plant Metabolite Spectral Library for Untargeted and Targeted Metabolomics.

Yangyang Li, Wei Zhu, Qingyuan Xiang, Jeongim Kim, Craig Dufresne, Yufeng Liu, Tianlai Li, Sixue Chen

Abstract read
In one paragraph

Article in International journal of molecular sciences, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
  4. Frontiers in fungal biology · 2026
    Article
  5. Article
  6. Progress in the Study of Chemical Constituents ofInternational journal of molecular sciences · 2025
    Article
  7. Article
  8. Comparative Biochemical and Pharmacodynamic Analyses ofPharmaceuticals (Basel, Switzerland) · 2024
    Article
  9. Advances in Molecular Plant Sciences.International journal of molecular sciences · 2024
    Article
  10. Article
  11. Chemical Composition of Methanol Extracts from Leaves and Flowers ofInternational journal of molecular sciences · 2024
    Article
  12. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Yangyang LiCollege of Horticulture, Shenyang Agricultural University, Shenyang 110866, China.
Wei ZhuDepartment of Biology, Genetics Institute, University of Florida, Gainesville, FL 32611, USA.ORCID 0000-0001-9582-3787
Qingyuan XiangDepartment of Biology, Genetics Institute, University of Florida, Gainesville, FL 32611, USA.
Jeongim KimHorticultural Sciences Department, University of Florida, Gainesville, FL 32610, USA.ORCID 0000-0002-5618-3948
Craig DufresneThermo Scientific Training Institute, West Palm Beach, FL 32407, USA.
Yufeng LiuCollege of Horticulture, Shenyang Agricultural University, Shenyang 110866, China.
Tianlai LiCollege of Horticulture, Shenyang Agricultural University, Shenyang 110866, China.
Sixue ChenDepartment of Biology, Genetics Institute, University of Florida, Gainesville, FL 32611, USA.ORCID 0000-0002-6690-7612

Funding

National Science Foundation 1920420United States Department of Agriculture 2020-67013-32700
6 · The paper itself

Abstract

Large-scale high throughput metabolomic technologies are indispensable components of systems biology in terms of discovering and defining the metabolite parts of the system. However, the lack of a plant metabolite spectral library limits the metabolite identification of plant metabolomic studies. Here, we have created a plant metabolite spectral library using 544 authentic standards, which increased the efficiency of identification for untargeted metabolomic studies. The process of creating the spectral library was described, and the mzVault library was deposited in the public repository for free download. Furthermore, based on the spectral library, we describe a process of creating a pseudo-targeted method, which was applied to a proof-of-concept study of Arabidopsis leaf extracts. As authentic standards become available, more metabolite spectra can be easily incorporated into the spectral library to improve the mzVault package.

Indexed as

MetabolomicsPlantsGene LibraryArabidopsismetabolomicsmzVaultpseudo-targeted methodspectral library

Identifiers

PMID36768571
PMCPMC9916794

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.