Evidence map›Paper›PMID 36768555›Full record

ReviewInternational journal of molecular sciences2023

Gut Microbiome Proteomics in Food Allergies.

Ana G Abril, Mónica Carrera, Ángeles Sánchez-Pérez, Tomás G Villa

Abstract readReview
In one paragraph

Review in International journal of molecular sciences, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Review
  3. Clinical Proteomics Applied to Food Allergy.Advances in experimental medicine and biology · 2026
    Review
  4. Article
  5. Article
  6. Article
  7. Review
  8. Article
  9. Review
  10. Review
  11. Article
  12. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Ana G AbrilDepartment of Microbiology and Parasitology, Faculty of Pharmacy, University of Santiago de Compostela, 15706 Santiago de Compostela, Spain.ORCID 0000-0002-9214-3273
Mónica CarreraDepartment of Food Technology, Spanish National Research Council, Marine Research Institute, 36208 Vigo, Spain.ORCID 0000-0003-2973-449X
Ángeles Sánchez-PérezSydney School of Veterinary Science, Faculty of Science, University of Sydney, Sydney, NSW 2006, Australia.
Tomás G VillaDepartment of Microbiology and Parasitology, Faculty of Pharmacy, University of Santiago de Compostela, 15706 Santiago de Compostela, Spain.ORCID 0000-0002-9282-6234

Funding

Plan Complementario en Ciencias Marinas (PCCM) funded by Ministry of Science and Innovation. (Activity 3.6.B. NANOSEAOMICS)Spanish ministery MCIN/AEI PID2019-103845RB-C21with European Union's NextGeneration EU funds postdoc grant under the "Plan de Recuperación Transformación" program funded by the Spanish Ministry of Universities
6 · The paper itself

Abstract

Food allergies (FA) have dramatically increased in recent years, particularly in developed countries. It is currently well-established that food tolerance requires the strict maintenance of a specific microbial consortium in the gastrointestinal (GI) tract microbiome as alterations in the gut microbiota can lead to dysbiosis, causing inflammation and pathogenic intestinal conditions that result in the development of FA. Although there is currently not enough knowledge to fully understand how the interactions between gut microbiota, host responses and the environment cause food allergies, recent advances in '-omics' technologies (i.e., proteomics, genomics, metabolomics) and in approaches involving systems biology suggest future headways that would finally allow the scientific understanding of the relationship between gut microbiome and FA. This review summarizes the current knowledge in the field of FA and insights into the future advances that will be achieved by applying proteomic techniques to study the GI tract microbiome in the field of FA and their medical treatment. Metaproteomics, a proteomics experimental approach of great interest in the study of GI tract microbiota, aims to analyze and identify all the proteins in complex environmental microbial communities; with shotgun proteomics, which uses liquid chromatography (LC) for separation and tandem mass spectrometry (MS/MS) for analysis, as it is the most promising technique in this field.

Indexed as

Food HypersensitivityGastrointestinal MicrobiomeMicrobiotaHumansProteomicsTandem Mass Spectrometryfood allergiesgastrointestinal trackmass spectrometrymetaproteomicsmicrobiotaproteomics

Identifiers

PMID36768555
PMCPMC9917015

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.