Evidence map›Paper›PMID 36768520›Full record

ReviewInternational journal of molecular sciences2023

The Cell-Specific Role of SHP2 in Regulating Bone Homeostasis and Regeneration Niches.

Jie Zhang, Chengxinyue Ye, Yufan Zhu, Jun Wang, Jin Liu

Abstract readReview
In one paragraph

Review in International journal of molecular sciences, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed.

  1. Article
  2. Special Issue "Cells and Molecules in Bone Remodeling and Repair".International journal of molecular sciences · 2025
    Article
  3. Review
  4. Article
  5. Article
  6. Aging · 2024
    Article
  7. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Jie ZhangLaboratory for Aging Research, State Key Laboratory of Biotherapy, National Clinical Research Center for Geriatrics, West China Hospital, Sichuan University, Chengdu 610041, China.ORCID 0000-0003-4342-6776
Chengxinyue YeLaboratory for Aging Research, State Key Laboratory of Biotherapy, National Clinical Research Center for Geriatrics, West China Hospital, Sichuan University, Chengdu 610041, China.ORCID 0000-0003-3028-4115
Yufan ZhuLaboratory for Aging Research, State Key Laboratory of Biotherapy, National Clinical Research Center for Geriatrics, West China Hospital, Sichuan University, Chengdu 610041, China.
Jun WangState Key Laboratory of Oral Diseases, National Clinical Research Center for Oral Diseases, Department of Orthodontics, West China Hospital of Stomatology, Sichuan University, Chengdu 610041, China.ORCID 0000-0002-9040-6295
Jin LiuLaboratory for Aging Research, State Key Laboratory of Biotherapy, National Clinical Research Center for Geriatrics, West China Hospital, Sichuan University, Chengdu 610041, China.

Funding

National Natural Science Foundation of China 81970967National Natural Science Foundation of China 82271019Research and Develop Program, West China Hospital of Stomatology Sichuan University RD-03-202101Sichuan Health Commission Medical Science and Technology Program 21ZD003
6 · The paper itself

Abstract

Src homology-2 containing protein tyrosine phosphatase (SHP2), encoded by

Indexed as

ChondromatosisMAP Kinase Signaling SystemAnimalsChondrocytesHedgehog ProteinsMiceProtein Tyrosine Phosphatase, Non-Receptor Type 11Signal TransductionTumor MicroenvironmentHedgehog ProteinsProtein Tyrosine Phosphatase, Non-Receptor Type 11bone microenvironmentbone remodelinghomeostasisSHP2SHP2 agonistSHP2 inhibitor

Identifiers

PMID36768520
PMCPMC9917188

What OpenQuestion holds

Textmetadata
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.