Evidence map›Paper›PMID 36768225›Full record

ArticleInternational journal of molecular sciences2023

Plasma-Generated Nitric Oxide Water Mediates Environmentally Transmitted Pathogenic Bacterial Inactivation via Intracellular Nitrosative Stress.

Shweta B Borkar, Manorma Negi, Neha Kaushik, Shaik Abdul Munnaf, Linh Nhat Nguyen, Eun Ha Choi, Nagendra Kumar Kaushik

Abstract read
In one paragraph

Article in International journal of molecular sciences, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed.

  1. Review
  2. Article
  3. Article
  4. Article
  5. Article
  6. Advancements in Plasma Agriculture: A Review of Recent Studies.International journal of molecular sciences · 2023
    Review
  7. Plasma Bioscience and Medicine Molecular Research.International journal of molecular sciences · 2023
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Shweta B BorkarPlasma Bioscience Research Center, Department of Electrical and Biological Physics, Kwangwoon University, Seoul 01897, Republic of Korea.ORCID 0000-0002-8433-1987
Manorma NegiPlasma Bioscience Research Center, Department of Electrical and Biological Physics, Kwangwoon University, Seoul 01897, Republic of Korea.ORCID 0000-0002-6492-0506
Neha KaushikDepartment of Biotechnology, College of Engineering, The University of Suwon, Hwaseong 18323, Republic of Korea.ORCID 0000-0001-8671-6779
Shaik Abdul MunnafPlasma Bioscience Research Center, Department of Electrical and Biological Physics, Kwangwoon University, Seoul 01897, Republic of Korea.ORCID 0000-0003-1128-9738
Linh Nhat NguyenLaboratory of Plasma Technology, Institute of Materials Science, Vietnam Academy of Science and Technology, 18 Hoang Quoc Viet, Hanoi 100000, Vietnam.ORCID 0000-0003-1967-3857
Eun Ha ChoiPlasma Bioscience Research Center, Department of Electrical and Biological Physics, Kwangwoon University, Seoul 01897, Republic of Korea.ORCID 0000-0001-5385-1878
Nagendra Kumar KaushikPlasma Bioscience Research Center, Department of Electrical and Biological Physics, Kwangwoon University, Seoul 01897, Republic of Korea.ORCID 0000-0002-4965-5046

Funding

National Reserach Foundation of Korea 2021R1A6A1A03038785, 2021R1F1A1055694
6 · The paper itself

Abstract

Over time, the proportion of resistant bacteria will increase. This is a major concern. Therefore, effective and biocompatible therapeutic strategies against these bacteria are urgently needed. Non-thermal plasma has been exhaustively characterized for its antibacterial activity. This study aims to investigate the inactivation efficiency and mechanisms of plasma-generated nitric oxide water (PG-NOW) on pathogenic water, air, soil, and foodborne Gram-negative and Gram-positive bacteria. Using a colony-forming unit assay, we found that PG-NOW treatment effectively inhibited the growth of bacteria. Moreover, the intracellular nitric oxide (NO) accumulation was evaluated by 4-amino-5-methylamino-2',7'-dichlorofluorescein diacetate (DAF-FM DA) staining. The reduction of viable cells unambiguously indicates the anti-microbial effect of PG-NOW. The

Indexed as

Nitric OxideNitrosative StressAnti-Bacterial AgentsBacteriaOxidative StressAnti-Bacterial AgentsNitric Oxideantibacterial activityintracellular nitrosative stressmembrane damagemicrowave plasmanitrogen speciesreactive oxygen

Identifiers

PMID36768225
PMCPMC9915551

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.