Evidence map›Paper›PMID 36768221›Full record

ArticleInternational journal of molecular sciences2023

Evaluation of the Cytotoxic Effect of Pd

Raquel C Laginha, Clara B Martins, Ana L C Brandão, Joana Marques, M Paula M Marques, Luís A E Batista de Carvalho, Inês P Santos, Ana L M Batista de Carvalho

Abstract read
In one paragraph

Article in International journal of molecular sciences, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
  4. PdJournal of medicinal chemistry · 2024
    Article
  5. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Raquel C LaginhaMolecular Physical-Chemistry R&D Unit, Department of Chemistry, University of Coimbra, 3004-535 Coimbra, Portugal.ORCID 0000-0002-2188-4015
Clara B MartinsMolecular Physical-Chemistry R&D Unit, Department of Chemistry, University of Coimbra, 3004-535 Coimbra, Portugal.
Ana L C BrandãoMolecular Physical-Chemistry R&D Unit, Department of Chemistry, University of Coimbra, 3004-535 Coimbra, Portugal.ORCID 0000-0002-1886-5016
Joana MarquesMolecular Physical-Chemistry R&D Unit, Department of Chemistry, University of Coimbra, 3004-535 Coimbra, Portugal.ORCID 0000-0002-7333-9158
M Paula M MarquesMolecular Physical-Chemistry R&D Unit, Department of Chemistry, University of Coimbra, 3004-535 Coimbra, Portugal.ORCID 0000-0002-8391-0055
Luís A E Batista de CarvalhoMolecular Physical-Chemistry R&D Unit, Department of Chemistry, University of Coimbra, 3004-535 Coimbra, Portugal.ORCID 0000-0002-8059-8537
Inês P SantosMolecular Physical-Chemistry R&D Unit, Department of Chemistry, University of Coimbra, 3004-535 Coimbra, Portugal.ORCID 0000-0003-2463-246X
Ana L M Batista de CarvalhoMolecular Physical-Chemistry R&D Unit, Department of Chemistry, University of Coimbra, 3004-535 Coimbra, Portugal.ORCID 0000-0003-1280-3321

Funding

Fundação para a Ciência e Tecnologia UIDB/00070/2020 & UIDP/00070/2020
6 · The paper itself

Abstract

Regarding the development of new antineoplastic agents, with a view to assess the selective antitumoral potential which aims at causing irreversible damage to cancer cells while preserving the integrity of their healthy counterparts, it is essential to evaluate the cytotoxic effects in both healthy and malignant human cell lines. In this study, a complex with two Pd(II) centers linked by the biogenic polyamine spermine (Pd

Indexed as

Antineoplastic AgentsProstatic NeoplasmsCisplatinHumansLipidsMaleSpectroscopy, Fourier Transform InfraredSpermineAntineoplastic AgentsCisplatinLipidsSperminecisplatinFTIR microspectroscopypalladium(II)prostate cancerRaman microspectroscopy

Identifiers

PMID36768221
PMCPMC9916163

What OpenQuestion holds

Textmetadata
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.