Evidence map›Paper›PMID 36767992›Full record

SynthesisInternational journal of environmental research and public health2023

The Nebulous Association between Cognitive Impairment and Falls in Older Adults: A Systematic Review of the Literature.

Victoire Leroy, Valérie Martinet, Oumashankar Nunkessore, Christel Dentel, Hélène Durand, David Mockler, François Puisieux, Bertrand Fougère, Yaohua Chen

Abstract readSystematic Review
In one paragraph

Synthesis in International journal of environmental research and public health, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Victoire LeroyDivision of Geriatric Medicine, Tours University Hospital, 37000 Tours, France.
Valérie MartinetDepartment of Geriatrics, Saint-Pierre Hospital, ULB, 1000 Brussels, Belgium.
Oumashankar NunkessoreDepartment of Geriatrics, Dunkerque Hospital, 59240 Dunkerque, France.
Christel DentelNeurology Practice, 67170 Brumath, France.
Hélène DurandDepartment of Neurology, Hautepierre Hospital, Strasbourg University Hospital, 67200 Strasbourg, France.
David MocklerMedical Library, Trinity Centre for the Health Sciences, St James' Hospital, D08 W9RT Dublin, Ireland.
François PuisieuxDepartment of Gerontology, Lille University Hospital, 59000 Lille, France.
Bertrand FougèreDivision of Geriatric Medicine, Tours University Hospital, 37000 Tours, France.
Yaohua ChenDepartment of Gerontology, Lille University Hospital, 59000 Lille, France.ORCID 0000-0003-1778-1790

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundIn older people, dementia is a well-established risk factor for falls. However, the association and the causal relationship between falls and the earlier stages of cognitive impairment remains unclear. The purpose of the study was to review the literature data on the association between falls and cognitive impairment, no dementia, including Mild Cognitive Impairment.

methodsAccording to PRISMA guidelines, we searched five electronic databases (EMBASE, Web of Science, Medline, CINAHL, and PsychINFO) for articles published between January 2011 and August 2022 on observational studies of older people with a cognitive assessment and/or cognitive impairment diagnosis and a recording of falls. Their quality was reviewed according to the STROBE checklist.

resultsWe selected 42 of the 4934 initially retrieved publications. In 24 retrospective studies, a statistically significant association between falls and cognitive status was found in only 15 of the 32 comparisons (47%). Of the 27 cross-sectional analyses in prospective studies, only eight (30%) were positive and significant. We counted four longitudinal analyses, half of which suggested a causal relationship between falls and cognitive impairment. The investigational methods varied markedly from one study to another.

conclusionIt is still not clear whether falls are associated with cognitive impairment, no dementia. Data in favor of a causal relationship are scarce. Further studies are needed to clarify their relationship.

Indexed as

Accidental FallsCognitive DysfunctionAgedCross-Sectional StudiesHumansProspective StudiesRetrospective Studiescognitive impairmentfallsgait disordersmild cognitive impairment

Identifiers

PMID36767992
PMCPMC9915123

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.