Evidence map›Paper›PMID 36767702›Full record

Trial reportInternational journal of environmental research and public health2023

Effects of Transcranial Pulse Stimulation (TPS) on Adults with Symptoms of Depression-A Pilot Randomized Controlled Trial.

Teris Cheung, Tim Man Ho Li, Yuen Shan Ho, Georg Kranz, Kenneth N K Fong, Sau Fong Leung, Simon Ching Lam, Wing Fai Yeung, Joyce Yuen Ting Lam, Kwan Hin Fong and 3 more

Abstract readRandomized Controlled Trial
PubMed Full text at PMC Publisher
In one paragraph

Trial report in International journal of environmental research and public health, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 32 papers, 6 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
32citing papers in PubMed, 6 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

32 citing papers in PubMed, 6 syntheses or guidelines pooled it.

  1. Pooled it
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  3. Pooled it
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  6. Pooled it
  7. Transcranial Pulse Stimulation Enhances Dexterity in Parkinson's Disease: A Randomized Sham-Controlled Trial.Movement disorders : official journal of the Movement Disorder Society · 2026
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  11. Review
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  17. Advances in the Clinical Application of Neurostimulation in Major Depression.Advances in experimental medicine and biology · 2026
    Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors.

Teris CheungSchool of Nursing, The Hong Kong Polytechnic University, Hong Kong SAR, China.ORCID 0000-0002-5878-9193
Tim Man Ho LiDepartment of Psychiatry, The Chinese University of Hong Kong, Hong Kong SAR, China.
Yuen Shan HoSchool of Nursing, The Hong Kong Polytechnic University, Hong Kong SAR, China.
Georg KranzDepartment of Rehabilitation Sciences, The Hong Kong Polytechnic University, Hong Kong SAR, China.ORCID 0000-0002-3892-1804
Kenneth N K FongDepartment of Rehabilitation Sciences, The Hong Kong Polytechnic University, Hong Kong SAR, China.
Sau Fong LeungSchool of Nursing, The Hong Kong Polytechnic University, Hong Kong SAR, China.ORCID 0000-0002-9570-9332
Simon Ching LamSchool of Nursing, Tung Wah College, Hong Kong SAR, China.ORCID 0000-0002-2982-9192
Wing Fai YeungSchool of Nursing, The Hong Kong Polytechnic University, Hong Kong SAR, China.
Joyce Yuen Ting LamSchool of Nursing, The Hong Kong Polytechnic University, Hong Kong SAR, China.ORCID 0000-0001-6445-6240
Kwan Hin FongSchool of Nursing, The Hong Kong Polytechnic University, Hong Kong SAR, China.
Roland BeisteinerDepartment of Neurology, Medical University of Vienna, 1090 Vienna, Austria.ORCID 0000-0002-6410-5990
Yu-Tao XiangUnit of Psychiatry, Department of Public Health and Medicinal Administration, Institute of Translational Medicine, University of Macau, Macao SAR, China.
Calvin Pak Wing ChengDepartment of Psychiatry, University of Hong Kong, Hong Kong SAR, China.ORCID 0000-0003-4457-1908

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Transcranial pulse stimulation (TPS) is a recent development in non-invasive brain stimulations (NIBS) that has been proven to be effective in terms of significantly improving Alzheimer patients' cognition, memory, and execution functions. Nonetheless, there is, currently, no trial evaluating the efficacy of TPS on adults with major depression disorder (MDD) nationwide. In this single-blinded, randomized controlled trial, a 2-week TPS treatment comprising six 30 min TPS sessions were administered to participants. Participants were randomized into either the TPS group or the Waitlist Control (WC) group, stratified by gender and age according to a 1:1 ratio. Our primary outcome was evaluated by the Hamilton depression rating scale-17 (HDRS-17). We recruited 30 participants that were aged between 18 and 54 years, predominantly female (73%), and ethnic Chinese from 1 August to 31 October 2021. Moreover, there was a significant group x time interaction (F(1, 28) = 18.8,

Indexed as

Major Depressive DisorderTranscranial Direct Current StimulationAdolescentAdultCognitionDepressionDouble-Blind MethodFemaleHumansMaleMiddle AgedPilot ProjectsTreatment OutcomeYoung Adultefficacymajor depressive disordernoninvasive brain stimulationtranscranial pulse stimulation

Identifiers

PMID36767702
PMCPMC9915638

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.