ReviewInternational journal of environmental research and public health2023
Early Origins of Chronic Obstructive Pulmonary Disease: Prenatal and Early Life Risk Factors.
Review in International journal of environmental research and public health, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 34 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
34 citing papers in PubMed, 44 citations in OpenAlex.
- Early-life liquefied petroleum gas cooking intervention and lung function in Guatemalan children: a randomized clinical trial.Annals of the American Thoracic Society · 2026Trial
- Early dysanapsis in experimental bronchopulmonary dysplasia: implications for lifelong lung disease.American journal of physiology. Lung cellular and molecular physiology · 2026Article
- Application of a uniaxial force by pulling the skin around the mammary gland may affect the orientation of the ducts and the length of the mammary ductal network: Findings from computational modeling and laboratory experiments.PLoS computational biology · 2026Article
- Predicting the progression risk of chronic obstructive pulmonary disease in high-risk individuals based on whole-lung radiomics and deep learning: a multicenter study.Journal of thoracic disease · 2026Article
- Tobacco smoking behavior and health outcomes among patients with chronic diseases: a comparative study of tobacco-producing and non-producing areas in southern Thailand.Scientific reports · 2026Article
- Treatable traits of small airway dysfunction in children with asthma and advances in small airway-targeted therapeutic research: a narrative review.Translational pediatrics · 2026Review
- The effect of industry-related air pollution on pulmonary function: A prospective, cross-sectional comparative study of industrial proximity and smoking status.The Journal of international medical research · 2026Article
- AI-powered TargetMap: Enabling system-level target discovery through full-path reasoning on a unified knowledge graph.iScience · 2026Article
- The Impact of Small-for-Gestational-Age on Pulmonary Function in Infancy, a Retrospective Cohort Study.Pediatric pulmonology · 2026Article
- Optimized primary organotypic culture from murine neonatal tracheal airway epithelial cells.American journal of physiology. Lung cellular and molecular physiology · 2026Article
- Beyond spirometry: understanding COPD origins to support a new diagnostic approach.ERJ open research · 2026Review
- As the twig is bent, so the tree grows: the importance of early life influences on lung growth and respiratory health.Translational pediatrics · 2026Article
- Lung function in adults born with very low birth weight from young to mid-adulthood.Pediatric research · 2026Article
- Longitudinal developmental trajectories of weight-standardized lung function in preterm (28-36 + 6 weeks) vs. term infants and independent perinatal risk factors: a single-center prospective cohort study.Frontiers in pediatrics · 2026Article
- Mitochondrial dysfunction and the regulatory cell death crosstalk network in chronic obstructive pulmonary disease: from oxidative stress mechanisms to targeted therapeutic strategies.Frontiers in immunology · 2026Review
- Unravelling the exposome of severe exacerbations of obstructive respiratory diseases in France.BMJ open respiratory research · 2025Article
- Chest CT imaging for differentiating normal, PRISm, and COPD in comparison with pulmonary function tests.La Radiologia medica · 2025Article
- A computed tomography-based lung radiomics nomogram to identify acute exacerbation of chronic obstructive pulmonary disease: a multi-institutional validation study.Journal of thoracic disease · 2025Article
- An Examination of Sex Differences and Cigarette Smoking as Predictors of COPD Prevalence and Incidence in Older US Adults.Nicotine & tobacco research : official journal of the Society for Research on Nicotine and Tobacco · 2025Article
- Article
Corrections and comments
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Authors and funding
7 authors at 3 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
The main risk factor for chronic obstructive pulmonary disease (COPD) is active smoking. However, a considerable amount of people with COPD never smoked, and increasing evidence suggests that adult lung disease can have its origins in prenatal and early life. This article reviews some of the factors that can potentially affect lung development and lung function trajectories throughout the lifespan from genetics and prematurity to respiratory tract infections and childhood asthma. Maternal smoking and air pollution exposure were also analyzed among the environmental factors. The adoption of preventive strategies to avoid these risk factors since the prenatal period may be crucial to prevent, delay the onset or modify the progression of COPD lung disease throughout life.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.