Evidence map›Paper›PMID 36767368›Full record

ArticleInternational journal of environmental research and public health2023

DNA Damage and Apoptosis as In-Vitro Effect Biomarkers of Titanium Dioxide Nanoparticles (TiO

Margherita Ferrante, Alfina Grasso, Rossella Salemi, Massimo Libra, Barbara Tomasello, Maria Fiore, Chiara Copat

Open access · goldAbstract read
In one paragraph

Article in International journal of environmental research and public health, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed, 1 pooled it
2.8field-weighted citation impact, top 9% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed, 1 synthesis or guideline pooled it, 29 citations in OpenAlex.

  1. Pooled it
  2. Article
  3. Article
  4. Article
  5. Article
  6. Article
  7. Review
  8. Current Research in Drug-Free Cancer Therapies.Bioengineering (Basel, Switzerland) · 2025
    Review
  9. Article
  10. Article
  11. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 1 institution in 1 country.

Margherita FerranteDepartment of Medical, Surgical and Advanced Technologies "G.F. Ingrassia", University of Catania, Via Santa Sofia 87, 95123 Catania, Italy.ORCID 0000-0001-7596-2464
Alfina GrassoDepartment of Medical, Surgical and Advanced Technologies "G.F. Ingrassia", University of Catania, Via Santa Sofia 87, 95123 Catania, Italy.
Rossella SalemiDepartment of Biomedical and Biotechnological Sciences, University of Catania, Via Santa Sofia 83, 95123 Catania, Italy.
Massimo LibraDepartment of Biomedical and Biotechnological Sciences, University of Catania, Via Santa Sofia 83, 95123 Catania, Italy.ORCID 0000-0002-7232-7737
Barbara TomaselloSection of Biochemistry, Department of Drug Science, University of Catania, 95125 Catania, Italy.ORCID 0000-0001-6049-942X
Maria FioreDepartment of Medical, Surgical and Advanced Technologies "G.F. Ingrassia", University of Catania, Via Santa Sofia 87, 95123 Catania, Italy.ORCID 0000-0002-7726-9329
Chiara CopatDepartment of Medical, Surgical and Advanced Technologies "G.F. Ingrassia", University of Catania, Via Santa Sofia 87, 95123 Catania, Italy.ORCID 0000-0002-2262-6050
University of Catania · IT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

This study investigated the DNA damage and apoptosis in colon cancer cells HCT-116 and Caco-2 induced by engineered titanium dioxide nanoparticles (TiO

Indexed as

Colonic NeoplasmsMetal NanoparticlesNanoparticlesApoptosisbcl-2-Associated X ProteinCaco-2 CellsDNA DamageFood AdditivesHCT116 CellsHumansTitaniumbcl-2-Associated X ProteinFood AdditivesTitaniumtitanium dioxideapoptosisCaco-2E171genotoxicityHCT-116metallic nanoparticlesTiO2

Identifiers

PMID36767368
PMCPMC9915631
OpenAlexW4317727087

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.