Evidence map›Paper›PMID 36767149›Full record

SynthesisInternational journal of environmental research and public health2023

A Meta-Analysis of the Influence on Inflammatory Factors in Type 2 Diabetes among Middle-Aged and Elderly Patients by Various Exercise Modalities.

Weijun Yang, Haotian Jiao, Yizhang Xue, Lishuo Wang, Ye Zhang, Boqian Wang, Ziyi Teng, Junyan Li, Haotian Zhao, Chang Liu

Open access · goldAbstract readMeta-AnalysisReview
PubMed Full text at PMC Publisher
In one paragraph

Synthesis in International journal of environmental research and public health, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed, 2 pooled it
6.2field-weighted citation impact, top 3% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 2 syntheses or guidelines pooled it, 29 citations in OpenAlex.

  1. Pooled it
  2. Pooled it
  3. Trial
  4. Review
  5. Review
  6. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 3 institutions in 1 country.

Weijun YangSports Coaching College, Beijing Sport University, Beijing 100084, China.
Haotian JiaoSports Coaching College, Beijing Sport University, Beijing 100084, China.ORCID 0000-0002-9048-3688
Yizhang XueSports Coaching College, Beijing Sport University, Beijing 100084, China.
Lishuo WangSchool of Management Engineering and E-Commerce, Zhejiang Gongshang University, Hangzhou 310018, China.
Ye ZhangSports Coaching College, Beijing Sport University, Beijing 100084, China.
Boqian WangTourism Management, Beijing Sport University, Beijing 100084, China.
Ziyi TengSchool of Sport Science, Beijing Sport University, Beijing 100084, China.
Junyan LiSchool of Sport Science, Beijing Sport University, Beijing 100084, China.
Haotian ZhaoDepartment of Physical Education, Jiangnan University, Wuxi 214122, China.
Chang LiuSchool of Sport Science, Beijing Sport University, Beijing 100084, China.ORCID 0000-0002-7867-6807
Beijing Sport University · CNJiangnan University · CNZhejiang Gongshang University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The purpose of this study was to investigate the effects of various exercise modalities on inflammatory factors in middle-aged and elderly patients with type 2 diabetes (MEPT2D), as lifestyle changes, such as physical activity and dietary modifications, are considered important in the prevention of type 2 diabetes. For the study methodology, Pubmed, CNKI, EBSCO, Wanfang Data, and Web of Science were selected for the search. The methodological quality of the included studies was assessed by the Cochrane Risk of Bias (ROB) tool, and statistically analyzed using the RevMan 5.4.1 analysis software, which included 18 investigations involving 853 study subjects. Meta-analysis findings indicated that aerobic training (AT), resistance training (RT), combined training (CT), and high-intensity interval training (HIIT) showed significant reductions in CRP, TNF-α, IL-6, and IL-10 levels in MEPT2D. Among them, HIIT was superior to other training modalities in reducing TNF-α levels, while CT was superior to AT, RT, and HIIT in decreasing IL-6, IL-10, and CRP in MEPT2D. Meanwhile, RT had limited effects in reducing CRP and TNF-α levels in MEPT2D. However, HIIT had no significant effect on IL-6 and IL-10 in MEPT2D. In conclusion, long-term regular AT, RT, CT, and HIIT all contributed to the reduction of inflammatory status (CRP, TNF-α, IL-6, and IL-10) in MEPT2D, while CT (for CRP, IL-6, and IL-10) and HIIT (for TNF-α) represent the best approaches to counteract the inflammatory response in MEPT2D.

Indexed as

Diabetes Mellitus, Type 2High-Intensity Interval TrainingResistance TrainingAgedHumansInterleukin-10Interleukin-6Middle AgedTumor Necrosis Factor-alphaInterleukin-10Interleukin-6Tumor Necrosis Factor-alphainflammationmeta-analysismiddle-aged and elderly patientstraining modalitiestype 2 diabetes

Identifiers

PMID36767149
PMCPMC9914443
OpenAlexW4317423657

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.