Evidence map›Paper›PMID 36766730›Full record

ArticleCells2023

HGCA2.0: An RNA-Seq Based Webtool for Gene Coexpression Analysis in

Vasileios L Zogopoulos, Apostolos Malatras, Konstantinos Kyriakidis, Chrysanthi Charalampous, Evanthia A Makrygianni, Stéphanie Duguez, Marianna A Koutsi, Marialena Pouliou, Christos Vasileiou, William J Duddy and 4 more

Abstract read
In one paragraph

Article in Cells, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

14 authors.

Vasileios L ZogopoulosCentre of Systems Biology, Biomedical Research Foundation, Academy of Athens, 11527 Athens, Greece.ORCID 0000-0002-4646-5570
Apostolos MalatrasBiobank.cy Center of Excellence in Biobanking and Biomedical Research, University of Cyprus, 2029 Nicosia, Cyprus.ORCID 0000-0003-1380-5521
Konstantinos KyriakidisCentre of Systems Biology, Biomedical Research Foundation, Academy of Athens, 11527 Athens, Greece.ORCID 0000-0002-1696-4838
Chrysanthi CharalampousCentre of Basic Research, Biomedical Research Foundation, Academy of Athens, 11527 Athens, Greece.
Evanthia A MakrygianniUniversity Research Institute of Maternal and Child Health and Precision Medicine, National and Kapodistrian University of Athens, 11527 Athens, Greece.
Stéphanie DuguezPersonalised Medicine Centre, School of Medicine, Ulster University, Derry-Londonderry BT47 6SB, UK.ORCID 0000-0001-6510-5426
Marianna A KoutsiCentre of Basic Research, Biomedical Research Foundation, Academy of Athens, 11527 Athens, Greece.ORCID 0000-0002-9182-5555
Marialena PouliouCentre of Basic Research, Biomedical Research Foundation, Academy of Athens, 11527 Athens, Greece.
Christos VasileiouCentre of Systems Biology, Biomedical Research Foundation, Academy of Athens, 11527 Athens, Greece.
William J DuddyPersonalised Medicine Centre, School of Medicine, Ulster University, Derry-Londonderry BT47 6SB, UK.ORCID 0000-0003-2239-9094
Marios AgelopoulosCentre of Basic Research, Biomedical Research Foundation, Academy of Athens, 11527 Athens, Greece.
George P ChrousosUniversity Research Institute of Maternal and Child Health and Precision Medicine, National and Kapodistrian University of Athens, 11527 Athens, Greece.ORCID 0000-0002-3098-5264
Vassiliki A IconomidouSection of Cell Biology and Biophysics, Department of Biology, National and Kapodistrian University of Athens, 15701 Athens, Greece.ORCID 0000-0002-9472-5146
Ioannis MichalopoulosCentre of Systems Biology, Biomedical Research Foundation, Academy of Athens, 11527 Athens, Greece.ORCID 0000-0001-8991-8712

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Genes with similar expression patterns in a set of diverse samples may be considered coexpressed. Human Gene Coexpression Analysis 2.0 (HGCA2.0) is a webtool which studies the global coexpression landscape of human genes. The website is based on the hierarchical clustering of 55,431

Indexed as

Gene Expression ProfilingGene Regulatory NetworksGenesHumansRNA-SeqTranscription FactorsTranscription Factorsbioinformaticsco-expressiongene coexpression analysisgene coexpression networkRNA-Seqtranscriptomicswebtool

Identifiers

PMID36766730
PMCPMC9913097

What OpenQuestion holds

Textmetadata
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Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.