Evidence map›Paper›PMID 36766723›Full record

SynthesisCells2023

Molecular Aspects of Allergen-Specific Immunotherapy in Patients with Seasonal Allergic Rhinitis.

Marina Izmailovich, Yuliya Semenova, Gulzada Abdushukurova, Ainur Mukhamejanova, Azhar Dyussupova, Raida Faizova, Meruert Gazaliyeva, Leila Akhvlediani, Natalya Glushkova, Sundetgali Kalmakhanov and 1 more

Open access · goldAbstract readSystematic Review
In one paragraph

Synthesis in Cells, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers.

0numbers the graph read from it
0cells of the map it votes in
15citing papers in PubMed
4.8field-weighted citation impact, top 4% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

15 citing papers in PubMed, 20 citations in OpenAlex.

  1. Comparative safety analysis of coseasonal versus preseasonal Artemisia annua sublingual immunotherapy for allergic rhinitis.European archives of oto-rhino-laryngology : official journal of the European Federation of Oto-Rhino-Laryngological Societies (EUFOS) : affiliated with the German Society for Oto-Rhino-Laryngology - Head and Neck Surgery · 2025
    Trial
  2. Review
  3. Article
  4. Article
  5. Article
  6. [Research status and hotspots of seasonal allergic rhinitis based on CiteSpace visualization analysis].Lin chuang er bi yan hou tou jing wai ke za zhi = Journal of clinical otorhinolaryngology head and neck surgery · 2026
    Article
  7. Article
  8. Article
  9. Article
  10. Article
  11. Article
  12. Review
  13. Review
  14. Article
  15. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 8 institutions in 3 countries.

Marina IzmailovichDepartment of Internal Diseases, Karaganda Medical University, Karaganda 100008, Kazakhstan.ORCID 0000-0001-8128-4356
Yuliya SemenovaSchool of Medicine, Nazarbayev University, Nur-Sultan 010000, Kazakhstan.ORCID 0000-0003-1324-7806
Gulzada AbdushukurovaDepartment of Therapy, Faculty of Postgraduate Medical Education, Shymkent Medical Institute, Shymkent 160006, Kazakhstan.
Ainur MukhamejanovaDepartment of Family Medicine No 2, Astana Medical University, Nur-Sultan 010000, Kazakhstan.
Azhar DyussupovaDepartment of General Medical Practice of Semey City, Semey Medical University, Semey 071400, Kazakhstan.ORCID 0000-0002-8857-4118
Raida FaizovaDepartment of General Medical Practice of Semey City, Semey Medical University, Semey 071400, Kazakhstan.
Meruert GazaliyevaVice-Rector for Clinical Work, Astana Medical University, Nur-Sultan 010000, Kazakhstan.
Leila AkhvledianiSchool of Medicine & Health Sciences, BAU International University Batumi, 6010 Batumi, Georgia.ORCID 0000-0002-7091-0187
Natalya GlushkovaDepartment of Epidemiology, Biostatistics & Evidence Based Medicine, Al-Farabi Kazakh National University, Almaty 050040, Kazakhstan.ORCID 0000-0003-1400-8436
Sundetgali KalmakhanovDepartment Health Policy and Organization, Al-Farabi Kazakh National University, Almaty 050040, Kazakhstan.
Geir BjørklundCouncil for Nutritional and Environmental Medicine (CONEM), 8610 Mo i Rana, Norway.ORCID 0000-0003-2632-3935
Al-Farabi Kazakh National University · KZAstana Medical University · KZSemey Medical University · KZBAU International University · USKaraganda Medical University · KZNazarbayev University · KZSouth Kazakhstan Medical Academy · KZThe Research Council of Norway · NO

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

A systematic review and narrative synthesis of publications was undertaken to analyze the role of component-resolved diagnosis technology in identifying polysensitization for the provision of allergen-specific immunotherapy to patients with seasonal allergic rhinitis. A search of publications was carried out in electronic databases in accordance with the Preferred Reporting Items for Systematic Reviews and Meta-Analyses guidelines. The search helped to identify 568 publications, 12 of which were included in this review. Overall, 3302 patients were enrolled. The major finding was that component-resolved diagnostics change the choice of relevant allergens for allergen-specific immunotherapy in at least 50% of cases. Sensitization to allergen components differs with age, type of disease, and overall disease duration. Patients who had both bronchial asthma and allergic rhinitis were sensitized to a larger number of allergens than patients who had bronchial asthma alone.

Indexed as

AsthmaRhinitis, AllergicRhinitis, Allergic, SeasonalAllergensDesensitization, ImmunologicHumansAllergensallergen-specific immunotherapycomponent-resolved diagnosticscross-reactivitymolecular allergy diagnosticsseasonal allergic rhinitissensitization

Identifiers

PMID36766723
PMCPMC9913438
OpenAlexW4317608987

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.