Evidence map›Paper›PMID 36766664›Full record

ReviewDiagnostics (Basel, Switzerland)2023

SARS-CoV-2 Omicron (B.1.1.529) Variant: A Challenge with COVID-19.

Zeinab Mohseni Afshar, Ali Tavakoli Pirzaman, Bardia Karim, Shiva Rahimipour Anaraki, Rezvan Hosseinzadeh, Elaheh Sanjari Pireivatlou, Arefeh Babazadeh, Dariush Hosseinzadeh, Seyed Rouhollah Miri, Terence T Sio and 3 more

Abstract readReview
In one paragraph

Review in Diagnostics (Basel, Switzerland), 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers.

0numbers the graph read from it
0cells of the map it votes in
16citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

16 citing papers in PubMed.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors.

Zeinab Mohseni AfsharClinical Research Development Center, Imam Reza Hospital, Kermanshah University of Medical Sciences, Kermanshah 51351, Iran.
Ali Tavakoli PirzamanStudent Research Committee, Babol University of Medical Sciences, Babol 47176-47745, Iran.
Bardia KarimStudent Research Committee, Babol University of Medical Sciences, Babol 47176-47745, Iran.
Shiva Rahimipour AnarakiFaculty of Medicine, Iran University of Medical Sciences, Tehran 14535, Iran.
Rezvan HosseinzadehStudent Research Committee, Babol University of Medical Sciences, Babol 47176-47745, Iran.
Elaheh Sanjari PireivatlouStudent Research Committee, Faculty of Pharmacy, Islamic Azad University, Ayatollah Amoli Branch, Amol 4615143358, Iran.
Arefeh BabazadehInfectious Diseases and Tropical Medicine Research Center, Health Research Institute, Babol University of Medical Sciences, Babol 47176-47745, Iran.
Dariush HosseinzadehBogomolets National Medical University, 01601 Kyiv, Ukraine.
Seyed Rouhollah MiriCancer Research Center, Canicer Institute of Iran, Tehran University of Medical Science, Tehran 1419733151, Iran.
Terence T SioDepartment of Radiation Oncology, Mayo Clinic, Phoenix, AZ 85054, USA.
Mark J M SullmanDepartment of Social Sciences, University of Nicosia, Nicosia 2417, Cyprus.ORCID 0000-0001-7920-6818
Mohammad BararyStudent Research Committee, Virtual School of Medical Education and Management, Shahid Beheshti University of Medical Sciences, Tehran 19839 69411, Iran.ORCID 0000-0001-8733-9370
Soheil EbrahimpourInfectious Diseases and Tropical Medicine Research Center, Health Research Institute, Babol University of Medical Sciences, Babol 47176-47745, Iran.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Since the beginning of the coronavirus disease 2019 (COVID-19) pandemic, there have been multiple peaks of the SARS-CoV-2 (severe acute respiratory syndrome coronavirus virus 2) infection, mainly due to the emergence of new variants, each with a new set of mutations in the viral genome, which have led to changes in the pathogenicity, transmissibility, and morbidity. The Omicron variant is the most recent variant of concern (VOC) to emerge and was recognized by the World Health Organization (WHO) on 26 November 2021. The Omicron lineage is phylogenetically distinct from earlier variants, including the previously dominant Delta SARS-CoV-2 variant. The reverse transcription-polymerase chain reaction (RT-PCR) test, rapid antigen assays, and chest computed tomography (CT) scans can help diagnose the Omicron variant. Furthermore, many agents are expected to have therapeutic benefits for those infected with the Omicron variant, including TriSb92, molnupiravir, nirmatrelvir, and their combination, corticosteroids, and interleukin-6 (IL-6) receptor blockers. Despite being milder than previous variants, the Omicron variant threatens many lives, particularly among the unvaccinated, due to its higher transmissibility, pathogenicity, and infectivity. Mounting evidence has reported the most common clinical manifestations of the Omicron variant to be fever, runny nose, sore throat, severe headache, and fatigue. This review summarizes the essential features of the Omicron variant, including its history, genome, transmissibility, clinical manifestations, diagnosis, management, and the effectiveness of existing vaccines against this VOC.

Indexed as

COVID-19omicronSARS-CoV-2variants of concern

Identifiers

PMID36766664
PMCPMC9913917

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.