Evidence map›Paper›PMID 36766609›Full record

ArticleDiagnostics (Basel, Switzerland)2023

Factors Associated with a Post-Procedure Spontaneous Pregnancy after a Hysterosapingo-Foam-Sonography (HyFoSy): Results from a Multicenter Observational Study.

Virginia Engels, Margarita Medina, Eugenia Antolín, Cristina Ros, Carmina Bermejo, Nabil Manzour, Irene Pelayo, Ainara Amaro, Pilar Martinez-Ten, Cristian De-Guirior and 7 more

Abstract read
In one paragraph

Article in Diagnostics (Basel, Switzerland), 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed.

  1. Nomogram-based predictive model for intra-myometrial contrast agent reflux using imaging features from 4D hysterosalpingo-contrast sonography.Zhong nan da xue xue bao. Yi xue ban = Journal of Central South University. Medical sciences · 2025
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

17 authors.

Virginia EngelsDepartment of Obstetrics and Gynecology, Hospital Universitario Puerta de Hierro, 28222 Majadahonda, Spain.
Margarita MedinaDepartment of Obstetrics and Gynecology, Hospital Universitario Materno-Infantil, Las Palmas de Gran, 35016 Canaria, Spain.ORCID 0000-0002-8508-3495
Eugenia AntolínDivision of Maternal and Fetal Medicine, Department of Obstetrics and Gynecology, Hospital Universitario La Paz. IdiPAZ, 28046 Madrid, Spain.
Cristina RosDepartment of Gynecology, Institut Clínic de Ginecologia, Obstetrícia, i Neonatologia, Hospital Clinic of Barcelona, University of Barcelona, 08036 Barcelona, Spain.
Carmina BermejoDelta Ecografía, Centro de Diagnóstico por la Imagen en Obstetricia, Ginecología y Mama, 28006 Madrid, Spain.
Nabil ManzourDepartment of Obstetrics and Gynecology, Clinica Universidad de Navarra, 31008 Pamplona, Spain.
Irene PelayoDepartment of Obstetrics and Gynecology, Hospital Universitario Ramón y Cajal, 28034 Madrid, Spain.ORCID 0000-0002-3532-5265
Ainara AmaroDepartment of Obstetrics and Gynecology, Hospital Universitario Materno-Infantil, Las Palmas de Gran, 35016 Canaria, Spain.ORCID 0000-0002-7022-6844
Pilar Martinez-TenDelta Ecografía, Centro de Diagnóstico por la Imagen en Obstetricia, Ginecología y Mama, 28006 Madrid, Spain.
Cristian De-GuiriorDepartment of Gynecology, Institut Clínic de Ginecologia, Obstetrícia, i Neonatologia, Hospital Clinic of Barcelona, University of Barcelona, 08036 Barcelona, Spain.
Roberto RodríguezDivision of Maternal and Fetal Medicine, Department of Obstetrics and Gynecology, Hospital Universitario La Paz. IdiPAZ, 28046 Madrid, Spain.ORCID 0000-0002-1953-2010
Laura SotilloDivision of Maternal and Fetal Medicine, Department of Obstetrics and Gynecology, Hospital Universitario La Paz. IdiPAZ, 28046 Madrid, Spain.
Isabel BrotonsDepartment of Obstetrics and Gynecology, Clinica Universidad de Navarra, 31008 Pamplona, Spain.
Reyes de la Cuesta-BenjumeaDepartment of Obstetrics and Gynecology, Hospital Universitario Puerta de Hierro, 28222 Majadahonda, Spain.
Oscar MartinezDepartment of Obstetrics and Gynecology, Hospital Universitario Puerta de Hierro, 28222 Majadahonda, Spain.ORCID 0000-0002-1457-3446
Javier SanchoDepartment of Obstetrics and Gynecology, Hospital Universitario Ramón y Cajal, 28034 Madrid, Spain.
Juan Luis AlcázarDepartment of Obstetrics and Gynecology, Clinica Universidad de Navarra, 31008 Pamplona, Spain.ORCID 0000-0002-9700-0853

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundTubal patency testing constitutes an essential part of infertility work-up. Hysterosalpingo-foam-sonography (HyFoSy) is currently one of the best tests for assessing tubal patency. The objective of our study was to evaluate the post-procedure rate of spontaneous pregnancy among infertile women submitted for an HyFoSy exam with ExEm

methodsMulticenter, prospective, observational study performed at six Spanish centers for gynecologic sonography and human reproduction. From December 2015 to June 2021, 799 infertile women underwent HyFoSy registration consecutively. The patients' information was collected from their medical records. Multivariable regression analyses were performed, controlling for age, etiology, and time of sterility. The main outcome was to measure post-procedure spontaneous pregnancy rates and the factors associated with the achievement of pregnancy.

results201 (26.5%) women got spontaneous conception (SC group), whereas 557 (73.5%) women did not get pregnant (non-spontaneous conception group, NSC). The median time for reaching SC after HyFoSy was 4 months (CI 95% 3.1-4.9), 18.9% of them occurring the same month of the procedure. Couples with less than 18 months of infertility were 93% more likely to get pregnant after HyFoSy (OR 1.93, 95% CI 1.34-2.81;

conclusionAfter HyFoSy, one in four patients got pregnant within the next twelve months. Couples with shorter infertility time, unexplained infertility, and women under 35 years are more likely to achieve SC after HyFoSy.

Indexed as

hysterosalpingo-foam-sonography (HyFoSy)infertilitypregnancyspontaneous conceptiontubal flushing effect

Identifiers

PMID36766609
PMCPMC9914236

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.