Evidence map›Paper›PMID 36766570›Full record

ArticleDiagnostics (Basel, Switzerland)2023

Active Surveillance of Root Caries in Vivo with CP-OCT.

Yihua Zhu, Minyoung Kim, Donald Curtis, Jing Wang, Oanh Le, Daniel Fried

Abstract read
In one paragraph

Article in Diagnostics (Basel, Switzerland), 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

  1. Article
  2. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Yihua ZhuDepartment of Preventive and Restorative Dental Sciences, University of California, San Francisco, 707 Parnassus Ave, San Francisco, CA 9414, USA.
Minyoung KimDepartment of Preventive and Restorative Dental Sciences, University of California, San Francisco, 707 Parnassus Ave, San Francisco, CA 9414, USA.ORCID 0000-0002-9502-1626
Donald CurtisDepartment of Preventive and Restorative Dental Sciences, University of California, San Francisco, 707 Parnassus Ave, San Francisco, CA 9414, USA.
Jing WangDepartment of Preventive and Restorative Dental Sciences, University of California, San Francisco, 707 Parnassus Ave, San Francisco, CA 9414, USA.
Oanh LeDepartment of Preventive and Restorative Dental Sciences, University of California, San Francisco, 707 Parnassus Ave, San Francisco, CA 9414, USA.
Daniel FriedDepartment of Preventive and Restorative Dental Sciences, University of California, San Francisco, 707 Parnassus Ave, San Francisco, CA 9414, USA.ORCID 0000-0002-5327-2558

Funding

National Institutes of Health R01-DE027335
6 · The paper itself

Abstract

The active surveillance of root caries lesions to monitor potential remineralization or decay progression is challenging for the clinician, due to unreliable diagnostic information. The conventional visual and tactile methods for assessing the lesion activity are not reliable, and the clinician is often unable to determine if the lesion is progressing or has been arrested. An important marker of an arrested lesion is a highly mineralized transparent surface zone (TSL) that forms when the mineral is deposited in the outer layer of the lesion. The purpose of this study was to determine if cross-polarization optical coherence tomography (CP-OCT) could be used to detect changes in the lesion severity and activity during active monitoring. In total, 18 subjects with 22 suspected active root caries lesions were evaluated using CP-OCT at the baseline, 3 months, and 6 months. All subjects were instructed to use a high fluoride dentifrice at the baseline. The results showed that CP-OCT was able to discriminate the active from the arrested lesions by identifying the presence of a TSL on arrested lesions. The results also indicated that the mean TSL thickness increased significantly (

Indexed as

lesion activitynon-surgical interventionoptical coherence tomographyroot caries

Identifiers

PMID36766570
PMCPMC9914565

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.