ArticleDiagnostics (Basel, Switzerland)2023
Multiple Pregnancy and the Risk of Postpartum Hemorrhage: Retrospective Analysis in a Tertiary Level Center of Care.
Article in Diagnostics (Basel, Switzerland), 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers, 1 of them a synthesis that pooled it.
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Who cites it
8 citing papers in PubMed, 1 synthesis or guideline pooled it.
- Twin pregnancy and postpartum haemorrhage: a systematic review and meta-analysis.BMC pregnancy and childbirth · 2024Pooled it
- Association between adverse obstetric history and perinatal outcomes in singleton and twin pregnancies: a retrospective study.Frontiers in medicine · 2026Article
- Association between pre-delivery bleeding tendency and postpartum bleeding severity: implications for rural and low-resource healthcare settings-a cohort study.Journal of rural medicine : JRM · 2026Article
- Development and validation of a postpartum hemorrhage risk prediction model for advanced maternal age women undergoing vaginal delivery: a comparison of multiple machine learning algorithms.Frontiers in medicine · 2026Article
- Evaluating the prognostic association between race and perineal trauma: a systematic review protocol.BMJ open · 2025Article
- Relationship between inter-pregnancy interval and risk of adverse maternal and neonatal outcomes in subsequent twin pregnancies.BMC pregnancy and childbirth · 2025Article
- Pregnancy and obstetric outcomes of dichorionic triamniotic triplet pregnancies with selective foetal reduction after assisted reproductive technology.Reproductive biology and endocrinology : RB&E · 2024Article
- Predictors of Postpartum Hemorrhage and Associated Outcomes at a Midwest Academic Medical Center.Women's health reports (New Rochelle, N.Y.) · 2024Article
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Authors and funding
9 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
The aim of our study was to identify characteristics associated with postpartum hemorrhage (PPH defined as blood loss >1000 mL) in twin pregnancies in order to select patients at higher risk to be treated. This retrospective study includes multiple pregnancies between 2015 and 2020. The possible association between pregnancy characteristics and the primary endpoint (occurrence of PPH) was conducted using chi-square or Fisher exact test and Wilcoxon test. Then, univariate logistic models were performed considering as outcome the PPH, and the odds ratios with 95% CI were estimated. Finally, a multivariate logistic model was implemented, including all significant covariates. Seven hundred seven twin pregnancies giving birth beyond 32 weeks were included and of those, 120 (16.97%) had a PPH. The univariate analysis showed that factors significantly associated with PPH were: Preterm delivery, episiotomy, neonatal weight, and mode of delivery. The multivariate analysis showed that the most important factors were episiotomy and neonatal weight. The results show that the performance of episiotomy and the neonatal weight are the factors that most impact the risk of PPH in twin pregnancies. The correct identification of factors associated with PPH in twins could ideally allow to modify the clinical management and positively affect the rate of complications.
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