Evidence map›Paper›PMID 36766399›Full record

ArticleAnimals : an open access journal from MDPI2023

Exploring the Relationship between Spontaneous Sister Chromatid Exchange and Genome Instability in Two Cryptic Species of Non-Human Primates.

Mariela Nieves, Fiona Puntieri, Susan M Bailey, Marta D Mudry, David G Maranon

Abstract read
In one paragraph

Article in Animals : an open access journal from MDPI, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Mariela NievesCentro de Investigación en Reproducción Humana y Experimental (CIRHE), Centro de Educación Médica e Investigaciones Clínicas (CEMIC), CONICET, Buenos Aires C1431-CABA, Argentina.
Fiona PuntieriGrupo de Investigación en Biología Evolutiva (GIBE), Departamento de Ecología, Genética y Evolución (DEGE), Facultad de Ciencias Exactas y Naturales, Universidad de Buenos Aires, Buenos Aires C1428-CABA, Argentina.ORCID 0000-0001-6444-6819
Susan M BaileyDepartment of Environmental and Radiological Health Sciences, Colorado State University, Fort Collins, CO 80521-1618, USA.
Marta D MudryGrupo de Investigación en Biología Evolutiva (GIBE), Departamento de Ecología, Genética y Evolución (DEGE), Facultad de Ciencias Exactas y Naturales, Universidad de Buenos Aires, Buenos Aires C1428-CABA, Argentina.
David G MaranonDepartment of Environmental and Radiological Health Sciences, Colorado State University, Fort Collins, CO 80521-1618, USA.

Funding

Fulbright Association Scholarship M NievesNational Scientific and Technical Research Council 0744Telomeres and Telomerase Laboratory S. Bailey
6 · The paper itself

Abstract

There are extensive studies on chromosome morphology and karyotype diversity in primates, yet we still lack insight into genomic instability as a key factor underlying the enormous interspecies chromosomal variability and its potential contribution to evolutionary dynamics. In this sense, the assessment of spontaneous sister chromatid exchange (SCE) frequencies represents a powerful tool for evaluating genome stability. Here, we employed G-banding, fluorescence plus Giemsa (FPG), and chromosome orientation fluorescence in situ hybridization (CO-FISH) methodologies to characterize both chromosome-specific frequencies of spontaneously occurring SCE throughout the genome (G-SCE) and telomere-specific SCE (T-SCE). We analyzed primary fibroblast cultures from two male species of

Indexed as

AtelesCO-FISHgenome instabilityG-SCEprimatesT-SCE

Identifiers

PMID36766399
PMCPMC9913470

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.