Evidence map›Paper›PMID 36765982›Full record

ReviewFoods (Basel, Switzerland)2023

Glycemic Responses of Milk and Plant-Based Drinks: Food Matrix Effects.

Blerina Shkembi, Thom Huppertz

Registry-linked trialAbstract readReview
In one paragraph

Review in Foods (Basel, Switzerland), 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT06082921 (Study of nUtrition in Postpartum and EaRly Life), which is not on this map. Cited by 15 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
15citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT06082921 nacompletednot on this map

Study of nUtrition in Postpartum and EaRly Life (SUPER): Beef Feeding Trial

TypeinterventionalSponsorUniversity of Texas at AustinRan2023 to 2024Enrolled24ConditionsGlycemic Response, Breast Feeding, Exclusive, Eating BehaviorArmsBeef Diet Intervention, Impossible Beef Diet Intervention
3 · Its place in the literature

Who cites it

15 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Trial
  3. Article
  4. Article
  5. Article
  6. Article
  7. US infant formulas contain primarily added sugars: An analysis of infant formulas on the US market.Journal of food composition and analysis : an official publication of the United Nations University, International Network of Food Data Systems · 2025
    Article
  8. Review
  9. Review
  10. Article
  11. Article
  12. Review
  13. Review
  14. Insights and Perspectives on Plant-Based Beverages.Plants (Basel, Switzerland) · 2023
    Review
  15. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors.

Blerina ShkembiFood Quality & Design Group, Wageningen University & Research, 6708WG Wageningen, The Netherlands.
Thom HuppertzFood Quality & Design Group, Wageningen University & Research, 6708WG Wageningen, The Netherlands.ORCID 0000-0003-4142-9359

Funding

Dutch Dairy Association 20/161
6 · The paper itself

Abstract

The consumption of food items containing digestible carbohydrates in food products leads to postprandial increases in blood glucose levels and glycemic responses. The extent to which these occur depends on many factors, including concentration and type of carbohydrate, but also other physicochemical properties of the food matrix, which determine the rate of uptake of monosaccharides into the bloodstream, including product structure and factors affecting gastric emptying. For milk, control of postprandial glycemic responses appears to be multifaceted, including a controlled rate of gastric emptying, a rate of glucose and galactose uptake into the bloodstream controlled by enzymatic hydrolysis, as well as stimulated insulin secretion to enhance uptake of blood glucose from the bloodstream. Altogether, this allows milk to deliver comparatively high levels of carbohydrate with limited glycemic responses. For plant-based drinks positioned as milk alternatives, however, compositional differences (including carbohydrate type and concentration) as well as matrix factors limiting control over gastric emptying and insulin secretion can, in some cases, lead to much stronger glycemic responses, which are undesirable in relation to non-communicable diseases, such as type-2 diabetes. This review discusses glycemic responses to milk and plant-based drinks from this perspective, focusing on mechanistic insights and food matrix effects.

Indexed as

carbohydratesdairy productsfood matrixglycemic indexglycemic loadmetabolismplant-based drinkspostprandial glycemic response

Identifiers

PMID36765982
PMCPMC9914410

What OpenQuestion holds

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Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.