Evidence map›Paper›PMID 36765915›Full record

ArticleCancers2023

Carfilzomib-Based Regimen and Cardiotoxicity in Multiple Myeloma: Incidence of Cardiovascular Events and Organ Damage in Carfilzomib-Dexamethasone versus Carfilzomib-Lenalidomide-Dexamethasone. A Real-Life Prospective Study.

Anna Astarita, Giulia Mingrone, Lorenzo Airale, Marco Cesareo, Anna Colomba, Cinzia Catarinella, Dario Leone, Francesca Gay, Sara Bringhen, Franco Veglio and 2 more

Abstract read
In one paragraph

Article in Cancers, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed.

  1. Observational
  2. Review
  3. Article
  4. Article
  5. Article
  6. Article
  7. Review
  8. Article
  9. Review
  10. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors.

Anna AstaritaHypertension Unit, Department of Medical Sciences, Division of Internal Medicine, AO "Città Della Salute e Della Scienza" University Hospital, 10126 Turin, Italy.
Giulia MingroneHypertension Unit, Department of Medical Sciences, Division of Internal Medicine, AO "Città Della Salute e Della Scienza" University Hospital, 10126 Turin, Italy.ORCID 0000-0002-7360-728X
Lorenzo AiraleHypertension Unit, Department of Medical Sciences, Division of Internal Medicine, AO "Città Della Salute e Della Scienza" University Hospital, 10126 Turin, Italy.ORCID 0000-0001-5407-5188
Marco CesareoHypertension Unit, Department of Medical Sciences, Division of Internal Medicine, AO "Città Della Salute e Della Scienza" University Hospital, 10126 Turin, Italy.
Anna ColombaHypertension Unit, Department of Medical Sciences, Division of Internal Medicine, AO "Città Della Salute e Della Scienza" University Hospital, 10126 Turin, Italy.
Cinzia CatarinellaHypertension Unit, Department of Medical Sciences, Division of Internal Medicine, AO "Città Della Salute e Della Scienza" University Hospital, 10126 Turin, Italy.
Dario LeoneHypertension Unit, Department of Medical Sciences, Division of Internal Medicine, AO "Città Della Salute e Della Scienza" University Hospital, 10126 Turin, Italy.
Francesca GayMyeloma Unit, Department of Medical Sciences, Division of Hematology, AO "Città Della Salute e Della Scienza" University Hospital, 10126 Turin, Italy.ORCID 0000-0002-8619-412X
Sara BringhenMyeloma Unit, Department of Medical Sciences, Division of Hematology, AO "Città Della Salute e Della Scienza" University Hospital, 10126 Turin, Italy.
Franco VeglioHypertension Unit, Department of Medical Sciences, Division of Internal Medicine, AO "Città Della Salute e Della Scienza" University Hospital, 10126 Turin, Italy.
Alberto MilanHypertension Unit, Department of Medical Sciences, Division of Internal Medicine, AO "Città Della Salute e Della Scienza" University Hospital, 10126 Turin, Italy.ORCID 0000-0002-8863-8572
Fabrizio VallelongaHypertension Unit, Department of Medical Sciences, Division of Internal Medicine, AO "Città Della Salute e Della Scienza" University Hospital, 10126 Turin, Italy.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Carfilzomib-mediated cardiotoxicity in multiple myeloma (MM) is a well-established adverse effect, however limited data are available on the comparison of cardiovascular complications in patients treated with Carfilzomib-dexamethasone (target dose of K 56 mg/m

Indexed as

cardiotoxicitycardiovascular adverse eventscarfilzomibdexamethasoneechocardiographyhypertensive eventsKdKRdlenalidomidemultiple myelomapulse wave velocityreal-life

Identifiers

PMID36765915
PMCPMC9913715

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.