Evidence map›Paper›PMID 36765880›Full record

ReviewCancers2023

Management of Recurrent Well-Differentiated Thyroid Carcinoma in the Neck: A Comprehensive Review.

Beatriz G Cavalheiro, Jatin P Shah, Gregory W Randolph, Jesus E Medina, Ralph P Tufano, Mark Zafereo, Dana M Hartl, Iain J Nixon, Orlando Guntinas-Lichius, Vincent Vander Poorten and 11 more

Open access · goldAbstract readReview
In one paragraph

Review in Cancers, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers.

0numbers the graph read from it
0cells of the map it votes in
16citing papers in PubMed
4.0field-weighted citation impact, top 5% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

16 citing papers in PubMed, 20 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

21 authors at 17 institutions in 11 countries.

Beatriz G CavalheiroCancer Institute of São Paulo State, Department of Head and Neck Surgery, University of São Paulo Medical School, Sao Paulo 01246-903, Brazil.ORCID 0000-0001-9720-5034
Jatin P ShahHead and Neck Service, Memorial Sloan Kettering Cancer Center, New York, NY 10065, USA.ORCID 0000-0002-6444-6592
Gregory W RandolphDepartment of Otolaryngology Head and Neck Surgery, Harvard Medical School, Boston, MA 02115, USA.ORCID 0000-0001-5373-9181
Jesus E MedinaDepartment of Otolaryngology and Head and Neck Surgery, University of Oklahoma College of Medicine, Oklahoma City, OK 73104, USA.
Ralph P TufanoMultidisciplinary Thyroid and Parathyroid Center, Head and Neck Endocrine Surgery, Sarasota Memorial Health Care System, Sarasota, FL 34239, USA.
Mark ZafereoDepartment of Head & Neck Surgery, MD Anderson Cancer Center, Houston, TX 77030, USA.ORCID 0000-0001-7918-9739
Dana M HartlDepartment of Surgery, Gustave Roussy, 94800 Villejuif, France.ORCID 0000-0003-1161-5628
Iain J NixonDepartment of Otolaryngology Head and Neck Surgery, NHS Lothian, University of Edinburgh, Edinburgh EH8 9YL, UK.
Orlando Guntinas-LichiusDepartment of Otorhinolaryngology-Head and Neck Surgery, Jena University Hospital, 07747 Jena, Germany.
Vincent Vander PoortenOtorhinolaryngology, Head and Neck Surgery, University Hospitals Leuven, 3000 Leuven, Belgium.ORCID 0000-0003-1341-829X
Fernando LópezENT and Head and Neck Department, Hospital Universitario Central de Asturias, University of Oviedo, ISPA, IUOPA, 33011 Oviedo, Spain.ORCID 0000-0001-7019-9746
Avi Hefetz KhafifAssuta Medical Center, Ben-Gurion University of the Negev, Tel Aviv 8436322, Israel.
Randall P OwenSection of Endocrine Surgery, Division of Surgical Oncology, Department of Surgery, Mount Sinai Hospital, Icahn School of Medicine, New York, NY 10029, USA.
Ashok ShahaHead and Neck Service, Department of Surgery, Memorial Sloan-Kettering Cancer Center, New York, NY 10065, USA.
Juan P RodrigoENT and Head and Neck Department, Hospital Universitario Central de Asturias, University of Oviedo, ISPA, IUOPA, 33011 Oviedo, Spain.ORCID 0000-0003-3063-0890
Alessandra RinaldoSchool of Medicine, University of Udine, 33100 Udine, Italy.ORCID 0000-0001-7956-6709
Antti A MäkitieDepartment of Otorhinolaryngology-Head and Neck Surgery, Helsinki University Hospital, University of Helsinki, 00290 Helsinki, Finland.ORCID 0000-0002-0451-2404
Carl E SilverDepartment of Surgery, University of Arizona College of Medicine, Phoenix, AZ 85724, USA.
Alvaro SanabriaDepartment of Surgery, School of Medicine, University of Antioquia, Medellín 0500100, Colombia.ORCID 0000-0002-5563-8840
Luiz P KowalskiDepartment of Head and Neck Surgery and Otorhinolaryngology, AC Camargo Cancer Center, Sao Paulo 01509-001, Brazil.ORCID 0000-0002-0481-156X
Alfio FerlitoCoordinator of the International Head and Neck Scientific Group, 35125 Padua, Italy.ORCID 0000-0002-8247-8002
Memorial Sloan Kettering Cancer Center · USUniversidad de Oviedo · ESUniversidade de São Paulo · BRBen-Gurion University of the Negev · ILHarvard University · USInstitut Gustave Roussy · FRJena University Hospital · DEKU Leuven · BEMount Sinai Hospital · USNHS Lothian · GBSarasota Memorial Health Care System · USThe University of Texas MD Anderson Cancer Center · USUniversidad de Antioquia · COUniversity of Arizona · USUniversity of Helsinki · FIUniversity of Oklahoma · USUniversity of Udine · IT

Funding

X-RAY CRYSTALLOGRAPHYP30CA008748 · NCI · SLOAN-KETTERING INSTITUTE FOR CANCER RES · PI Nicholas D Socci · 1985 to 2026
$347.4M
NCI NIH HHS P30 CA008748
6 · The paper itself

Abstract

Surgery has been historically the preferred primary treatment for patients with well-differentiated thyroid carcinoma and for selected locoregional recurrences. Adjuvant therapy with radioactive iodine is typically recommended for patients with an intermediate to high risk of recurrence. Despite these treatments, locally advanced disease and locoregional relapses are not infrequent. These patients have a prolonged overall survival that may result in long periods of active disease and the possibility of requiring subsequent treatments. Recently, many new options have emerged as salvage therapies. This review offers a comprehensive discussion and considerations regarding surgery, active surveillance, radioactive iodine therapy, ultrasonography-guided percutaneous ablation, external beam radiotherapy, and systemic therapy for well-differentiated thyroid cancer based on relevant publications and current reference guidelines. We feel that the surgical member of the thyroid cancer management team is empowered by being aware and facile with all management options.

Indexed as

metastasismolecular targeted therapyneck dissectionneoadjuvant therapypapillary thyroid cancerradiofrequency ablationradiotherapyrecurrencesurgerythyroid neoplasm

Identifiers

PMID36765880
PMCPMC9913047
OpenAlexW4318817246

What OpenQuestion holds

Textmetadata
LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.