Evidence map›Paper›PMID 36765864›Full record

ArticleCancers2023

Multi-Fold Computational Analysis to Discover Novel Putative Inhibitors of Isethionate Sulfite-Lyase (Isla) from

Muhammad Waqas, Sobia Ahsan Halim, Atta Ullah, Assim Alaa Mohammed Ali, Asaad Khalid, Ashraf N Abdalla, Ajmal Khan, Ahmed Al-Harrasi

Abstract read
In one paragraph

Article in Cancers, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed.

  1. Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Muhammad WaqasNatural and Medical Sciences Research Center, University of Nizwa, Birkat Al Mauz, P.O. Box 33, Nizwa 616, Oman.ORCID 0000-0001-6115-9689
Sobia Ahsan HalimNatural and Medical Sciences Research Center, University of Nizwa, Birkat Al Mauz, P.O. Box 33, Nizwa 616, Oman.ORCID 0000-0001-8526-7799
Atta UllahNatural and Medical Sciences Research Center, University of Nizwa, Birkat Al Mauz, P.O. Box 33, Nizwa 616, Oman.
Assim Alaa Mohammed AliNatural and Medical Sciences Research Center, University of Nizwa, Birkat Al Mauz, P.O. Box 33, Nizwa 616, Oman.
Asaad KhalidSubstance Abuse and Toxicology Research Center, Jazan University, P.O. Box 114, Jazan 45142, Saudi Arabia.ORCID 0000-0001-8734-2588
Ashraf N AbdallaDepartment of Pharmacology and Toxicology, College of Pharmacy, Umm Al-Qura University, P.O. Box 715, Makkah 21955, Saudi Arabia.ORCID 0000-0003-4770-9319
Ajmal KhanNatural and Medical Sciences Research Center, University of Nizwa, Birkat Al Mauz, P.O. Box 33, Nizwa 616, Oman.
Ahmed Al-HarrasiNatural and Medical Sciences Research Center, University of Nizwa, Birkat Al Mauz, P.O. Box 33, Nizwa 616, Oman.ORCID 0000-0002-0815-5942

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

A glycal radical enzyme called isethionate sulfite-lyase (Isla) breaks the C-S bond in isethionate to produce acetaldehyde and sulfite. This enzyme was found in the Gram-negative, colonial

Indexed as

Bilophila wadsworthiacolitiscolorectal cancerglycal radical enzymekeyword

Identifiers

PMID36765864
PMCPMC9913583

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.