Evidence map›Paper›PMID 36765852›Full record

ArticleCancers2023

Combining sCD163 with CA 19-9 Increases the Predictiveness of Pancreatic Ductal Adenocarcinoma.

Liva K Stuhr, Kasper Madsen, Astrid Z Johansen, Inna M Chen, Carsten P Hansen, Lars H Jensen, Torben F Hansen, Kirstine Kløve-Mogensen, Kaspar R Nielsen, Julia S Johansen

Abstract read
In one paragraph

Article in Cancers, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed.

  1. Research progress in diagnosis and treatment of pancreatic cancer with mismatch repair and microsatellite instability.Clinical & translational oncology : official publication of the Federation of Spanish Oncology Societies and of the National Cancer Institute of Mexico · 2026
    Review
  2. Study of serum tumor markers in the early diagnosis of pancreatic cancer.World journal of gastrointestinal oncology · 2025
    Article
  3. Review
  4. Article
  5. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Liva K StuhrDepartment of Oncology, Copenhagen University Hospital-Herlev and Gentofte, DK-2730 Herlev, Denmark.
Kasper MadsenDepartment of Oncology, Copenhagen University Hospital-Herlev and Gentofte, DK-2730 Herlev, Denmark.
Astrid Z JohansenDepartment of Oncology, Copenhagen University Hospital-Herlev and Gentofte, DK-2730 Herlev, Denmark.ORCID 0000-0002-4948-6799
Inna M ChenDepartment of Oncology, Copenhagen University Hospital-Herlev and Gentofte, DK-2730 Herlev, Denmark.ORCID 0000-0003-2891-0762
Carsten P HansenDepartment of Surgery, Copenhagen University Hospital-Rigshospitalet, DK-2200 Copenhagen, Denmark.ORCID 0000-0002-9256-2240
Lars H JensenDepartment of Oncology, University Hospital of Southern Denmark, DK-7100 Vejle, Denmark.ORCID 0000-0002-0020-1537
Torben F HansenDepartment of Oncology, University Hospital of Southern Denmark, DK-7100 Vejle, Denmark.ORCID 0000-0001-7476-671X
Kirstine Kløve-MogensenDepartment of Clinical Immunology, Aalborg University Hospital, DK-9000 Aalborg, Denmark.ORCID 0000-0003-4095-8291
Kaspar R NielsenDepartment of Clinical Immunology, Aalborg University Hospital, DK-9000 Aalborg, Denmark.
Julia S JohansenDepartment of Oncology, Copenhagen University Hospital-Herlev and Gentofte, DK-2730 Herlev, Denmark.ORCID 0000-0002-4217-6560

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The objective of this study was to evaluate the diagnostic and prognostic potential of soluble CD163 (sCD163) in patients with pancreatic ductal adenocarcinoma (PDAC). Preoperative serum samples from 255 patients with PDAC were analyzed for sCD163 using a commercially available enzyme-linked immunosorbent assay. The diagnostic value of sCD163 was evaluated using receiver operating characteristic (ROC) curves. The prognostic significance of sCD163 was evaluated by Cox regression analysis and Kaplan-Meier survival curves. sCD163 was significantly increased in patients with PDAC, across all stages, compared to healthy subjects (stage 1:

Indexed as

biomarkerpancreatic cancersoluble CD163tumor-associated macrophages

Identifiers

PMID36765852
PMCPMC9913074

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.