Evidence map›Paper›PMID 36765843›Full record

ArticleCancers2023

Elevation of Cytoplasmic Calcium Suppresses Microtentacle Formation and Function in Breast Tumor Cells.

Katarina T Chang, Keyata N Thompson, Stephen J P Pratt, Julia A Ju, Rachel M Lee, Trevor J Mathias, Makenzy L Mull, David A Annis, Eleanor C Ory, Megan B Stemberger and 2 more

Open access · goldAbstract read
In one paragraph

Article in Cancers, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
0.9field-weighted citation impact, top 21% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 4 citations in OpenAlex.

  1. The Pro-Metastatic Roles of ROS.Antioxidants (Basel, Switzerland) · 2026
    Review
  2. Review
  3. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors at 1 institution in 1 country.

Katarina T ChangGraduate Program in Molecular Medicine, University of Maryland School of Medicine, 800 W. Baltimore St., Baltimore, MD 21201, USA.ORCID 0000-0001-5431-6957
Keyata N ThompsonMarlene and Stewart Greenebaum NCI Comprehensive Cancer Center, University of Maryland School of Medicine, 655 W. Baltimore St., Baltimore, MD 21201, USA.
Stephen J P PrattMarlene and Stewart Greenebaum NCI Comprehensive Cancer Center, University of Maryland School of Medicine, 655 W. Baltimore St., Baltimore, MD 21201, USA.ORCID 0000-0003-3627-7258
Julia A JuGraduate Program in Molecular Medicine, University of Maryland School of Medicine, 800 W. Baltimore St., Baltimore, MD 21201, USA.ORCID 0000-0002-6395-4501
Rachel M LeeMarlene and Stewart Greenebaum NCI Comprehensive Cancer Center, University of Maryland School of Medicine, 655 W. Baltimore St., Baltimore, MD 21201, USA.ORCID 0000-0001-9359-0422
Trevor J MathiasGraduate Program in Molecular Medicine, University of Maryland School of Medicine, 800 W. Baltimore St., Baltimore, MD 21201, USA.ORCID 0000-0002-2830-8475
Makenzy L MullGraduate Program in Molecular Medicine, University of Maryland School of Medicine, 800 W. Baltimore St., Baltimore, MD 21201, USA.
David A AnnisMarlene and Stewart Greenebaum NCI Comprehensive Cancer Center, University of Maryland School of Medicine, 655 W. Baltimore St., Baltimore, MD 21201, USA.ORCID 0000-0001-6167-5819
Eleanor C OryMarlene and Stewart Greenebaum NCI Comprehensive Cancer Center, University of Maryland School of Medicine, 655 W. Baltimore St., Baltimore, MD 21201, USA.
Megan B StembergerMarlene and Stewart Greenebaum NCI Comprehensive Cancer Center, University of Maryland School of Medicine, 655 W. Baltimore St., Baltimore, MD 21201, USA.
Michele I VitoloMarlene and Stewart Greenebaum NCI Comprehensive Cancer Center, University of Maryland School of Medicine, 655 W. Baltimore St., Baltimore, MD 21201, USA.ORCID 0000-0001-8055-9645
Stuart S MartinMarlene and Stewart Greenebaum NCI Comprehensive Cancer Center, University of Maryland School of Medicine, 655 W. Baltimore St., Baltimore, MD 21201, USA.ORCID 0000-0002-4378-4381
University of Maryland, Baltimore · US

Funding

UNIVERSITY OF MARYLAND GREENEBAUM CANCER CENTERSUPPORT GRANTP30CA134274 · NCI · UNIVERSITY OF MARYLAND BALTIMORE · PI Vu H. Duong · 2008 to 2026
$51.0M
Training Grant in Cancer BiologyT32CA154274 · NCI · UNIVERSITY OF MARYLAND BALTIMORE · PI Toni M Antalis, CURT I CIVIN · 2011 to 2026
$6.8M
Tubulin microtentacles in detached mammary epithelial cellsR01CA124704 · NCI · UNIVERSITY OF MARYLAND BALTIMORE · PI MARTIN, STUART S · 2007 to 2025
$5.7M
TRAINING PROGRAM IN INTEGRATIVE MEMBRANE BIOLOGYT32GM008181 · NIGMS · UNIVERSITY OF MARYLAND BALTIMORE · PI RIZZO, MEGAN A, TRUDEAU, MATTHEW C · 1987 to 2022
$4.9M
Targeting microtubule stabilization to reduce breast tumor metastasisR01CA154624 · NCI · UNIVERSITY OF MARYLAND BALTIMORE · PI MARTIN, STUART S · 2012 to 2023
$3.4M
Medical Scientist Training ProgramT32GM092237 · NIGMS · UNIVERSITY OF MARYLAND BALTIMORE · PI ROGHMANN, MARY-CLAIRE · 2010 to 2019
$3.0M
Mechanism of Action by mTOR Kinase Inhibitors in Colorectal CancerR01CA166575 · NCI · UNIV OF MED/DENT NJ-R W JOHNSON MED SCH · PI ZHENG, STEVEN · 2012 to 2016
$1.6M
Rapid analysis of patient tumor cell drug responses to reduce metastatic riskI01BX002746 · VA · BALTIMORE VA MEDICAL CENTER · PI MARTIN, STUART S · 2019 to 2024
–
BLRD VA I01 BX002746NCI NIH HHS 5T32CA154274NCI NIH HHS K01CA166575NCI NIH HHS P30 CA134274NCI NIH HHS R01 CA124704NCI NIH HHS R01 CA154624NCI NIH HHS R01 CA166575NCI NIH HHS T32 CA154274NIGMS NIH HHS 5T32GM008181-30NIGMS NIH HHS 5T32GM092237NIGMS NIH HHS T32 GM008181NIGMS NIH HHS T32 GM092237NIH HHS R01-CA124704NIH HHS R01-CA154624
6 · The paper itself

Abstract

Cytoskeletal remodeling in circulating tumor cells (CTCs) facilitates metastatic spread. Previous oncology studies examine sustained aberrant calcium (Ca

Indexed as

breast cancercalcium (Ca2+)Ionomycin (Iono)metastasismicrotentacle (McTN)Thapsigargin (Tg)

Identifiers

PMID36765843
PMCPMC9913253
OpenAlexW4318776816

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.