Evidence map›Paper›PMID 36765832›Full record

ArticleCancers2023

Intraoperative Autofluorescence Imaging for Parathyroid Gland Identification during Total Laryngectomy with Thyroidectomy.

Raïs Obongo Anga, Muriel Abbaci, Joanne Guerlain, Ingrid Breuskin, Odile Casiraghi, Alix Marhic, Nadia Benmoussa-Rebibo, Héloïse de Kermadec, Antoine Moya-Plana, Stéphane Temam and 2 more

Abstract read
In one paragraph

Article in Cancers, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors.

Raïs Obongo AngaDepartment of Head and Neck Oncology, Gustave Roussy Cancer Campus, 94805 Villejuif, France.
Muriel AbbaciPlateforme d'Imagerie et de Cytométrie, UMS AMMICa, Gustave-Roussy Cancer Campus-Grand Paris, Université Paris-Saclay, 94805 Villejuif, France; Laboratoire d'Imagerie Biomédicale Multimodale Paris Saclay, Université Paris-Saclay, CEA, CNRS, Inserm, 91401 Orsay, France.ORCID 0000-0002-8408-8868
Joanne GuerlainDepartment of Head and Neck Oncology, Gustave Roussy Cancer Campus, 94805 Villejuif, France.
Ingrid BreuskinDepartment of Head and Neck Oncology, Gustave Roussy Cancer Campus, 94805 Villejuif, France.
Odile CasiraghiDepartment of Pathology, Gustave Roussy Cancer Campus, 94805 Villejuif, France.
Alix MarhicDepartment of Head and Neck Oncology, Gustave Roussy Cancer Campus, 94805 Villejuif, France.ORCID 0000-0002-9437-0744
Nadia Benmoussa-RebiboDepartment of Head and Neck Oncology, Gustave Roussy Cancer Campus, 94805 Villejuif, France.
Héloïse de KermadecDepartment of Head and Neck Oncology, Gustave Roussy Cancer Campus, 94805 Villejuif, France.
Antoine Moya-PlanaDepartment of Head and Neck Oncology, Gustave Roussy Cancer Campus, 94805 Villejuif, France.ORCID 0000-0003-1260-1762
Stéphane TemamDepartment of Head and Neck Oncology, Gustave Roussy Cancer Campus, 94805 Villejuif, France.
Philippe GorpheDepartment of Head and Neck Oncology, Gustave Roussy Cancer Campus, 94805 Villejuif, France.ORCID 0000-0001-7604-4964
Dana M HartlDepartment of Head and Neck Oncology, Gustave Roussy Cancer Campus, 94805 Villejuif, France.ORCID 0000-0003-1161-5628

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectiveHypoparathyroidism is a known complication of total laryngectomy, although parathyroid preservation and/or reimplantation are not routine. Autofluorescence is a new technique for identifying parathyroid glands intraoperatively. The aim of this study was to evaluate the feasibility of autofluorescence in this context. MATERIALS AND

methodsA retrospective study of patients undergoing total laryngectomy/pharyngectomy with concomitant thyroidectomy using the Fluobeam

resultsEighteen patients (16 males, median age 67) underwent total laryngectomy/pharyngectomy with total thyroidectomy (n = 12) or hemithyroidectomy (n = 6). A median of 2 parathyroid glands were identified per patient. Ninety-two percent were identified by autofluorescence before visualisation. All parathyroids were reimplanted due to devascularization. Temporary hypoparathyroidism occurred in nine patients, and was permanent in one patient. After 34 months of median follow-up (range 1-49), no tumor recurrence was observed in the reimplantation sites.

conclusionsTo our knowledge, this is the largest study to evaluate autofluorescence during total laryngectomy with thyroidectomy. No tumor recurrence occurred in the sites of parathyroid reimplantation.

Indexed as

autofluorescencelaryngectomyparathyroid glandsparathyroid reimplantationsquamous cell carcinomathyroidectomy

Identifiers

PMID36765832
PMCPMC9913419

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