Evidence map›Paper›PMID 36765781›Full record

ArticleCancers2023

Radiomics-Based Inter-Lesion Relation Network to Describe [

Lara Cavinato, Martina Sollini, Alessandra Ragni, Francesco Bartoli, Roberta Zanca, Francesco Pasqualetti, Andrea Marciano, Francesca Ieva, Paola Anna Erba

Abstract read
In one paragraph

Article in Cancers, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed.

  1. Article
  2. Article
  3. Radiomic-based prediction of lesion-specific systemic treatment response in metastatic disease.Computerized medical imaging and graphics : the official journal of the Computerized Medical Imaging Society · 2024
    Article
  4. Article
  5. Radiomic-Based Approaches in the Multi-metastatic Setting: A Quantitative Review.medRxiv : the preprint server for health sciences · 2024
    Article
  6. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Lara CavinatoMOX-Modeling and Scientific Computing, Department of Mathematics, Politecnico di Milano, p.zza Leonardo da Vinci 32, 20133 Milan, Italy.ORCID 0000-0001-7007-0205
Martina SolliniDepartment of Biomedical Sciences, Humanitas University, Via R. Levi Montalcini 4, 20090 Pieve Emanuele, Italy.ORCID 0000-0003-2214-6492
Alessandra RagniMOX-Modeling and Scientific Computing, Department of Mathematics, Politecnico di Milano, p.zza Leonardo da Vinci 32, 20133 Milan, Italy.ORCID 0000-0002-3647-7340
Francesco BartoliNuclear Medicine, Department of Translational Research and Advanced Technology in Medicine and Surgery, Pisa University Hospital, University of Pisa, Via Roma 67, 56123 Pisa, Italy.ORCID 0000-0002-2702-3259
Roberta ZancaDepartment of Biomedical Sciences, Humanitas University, Via R. Levi Montalcini 4, 20090 Pieve Emanuele, Italy.
Francesco PasqualettiRadiation Oncology, Pisa University Hospital, Via Roma 67, 56123 Pisa, Italy.ORCID 0000-0002-0788-1205
Andrea MarcianoNuclear Medicine, Department of Translational Research and Advanced Technology in Medicine and Surgery, Pisa University Hospital, University of Pisa, Via Roma 67, 56123 Pisa, Italy.
Francesca IevaMOX-Modeling and Scientific Computing, Department of Mathematics, Politecnico di Milano, p.zza Leonardo da Vinci 32, 20133 Milan, Italy.ORCID 0000-0003-0165-1983
Paola Anna ErbaNuclear Medicine, Department of Translational Research and Advanced Technology in Medicine and Surgery, Pisa University Hospital, University of Pisa, Via Roma 67, 56123 Pisa, Italy.

Funding

Italian Association for Cancer Research IG2017 Id.20819
6 · The paper itself

Abstract

Advanced image analysis, including radiomics, has recently acquired recognition as a source of biomarkers, although there are some technical and methodological challenges to face for its application in the clinic. Among others, proper phenotyping of metastatic or systemic disease where multiple lesions coexist is an issue, since each lesion contributes to characterization of the disease. Therefore, the radiomic profile of each lesion should be modeled into a more complex architecture able to reproduce each "unit" (lesion) as a part of the "entire" (patient). This work aimed to characterize intra-tumor heterogeneity underpinning metastatic prostate cancer using an exhaustive innovative approach which consist of a i) feature transformation method to build an agnostic (i.e., irrespective of pre-existence knowledge, experience, and expertise) radiomic profile of lesions extracted from [

Indexed as

imaging-derived biomarkersPETprostate cancerradiomicstumor heterogeneity

Identifiers

PMID36765781
PMCPMC9913254

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.