Evidence map›Paper›PMID 36765747›Full record

ArticleCancers2023

Gene-Transcript Expression in Urine Supernatant and Urine Cell-Sediment Are Different but Equally Useful for Detecting Prostate Cancer.

Marcelino Yazbek Hanna, Mark Winterbone, Shea P O'Connell, Mireia Olivan, Rachel Hurst, Rob Mills, Colin S Cooper, Daniel S Brewer, Jeremy Clark

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Cancers, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Article
  3. Article
  4. Article
  5. Article
  6. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Marcelino Yazbek HannaUrology Department Castle Hill, Hull University Teaching Hospital, Castle Rd, Cottingham HU16 5JQ, UK.
Mark WinterboneNorwich Medical School, University of East Anglia, Norwich NR4 7TJ, UK.
Shea P O'ConnellNorwich Medical School, University of East Anglia, Norwich NR4 7TJ, UK.ORCID 0000-0002-2850-3908
Mireia OlivanTranslational Oncology Laboratory, Department of Pathology and Experimental Therapy, School of Medicine, Universitat de Barcelona, 08907 L'Hospitalet de Llobregat, Spain.
Rachel HurstNorwich Medical School, University of East Anglia, Norwich NR4 7TJ, UK.
Rob MillsNorfolk and Norwich University Hospitals NHS Foundation Trust, Norwich NR4 7UY, UK.ORCID 0000-0002-9296-5066
Colin S CooperNorwich Medical School, University of East Anglia, Norwich NR4 7TJ, UK.
Daniel S BrewerNorwich Medical School, University of East Anglia, Norwich NR4 7TJ, UK.ORCID 0000-0003-4753-9794
Jeremy ClarkNorwich Medical School, University of East Anglia, Norwich NR4 7TJ, UK.

Funding

Big C Cancer Charity 19-07RMovember Foundation GAP1 Urine BiomarkersProstate Cancer UK RIA18-ST2-014The Andy Ripley Memorial Fund NAThe Bob Champion Cancer Trust NAthe King family NAThe Masonic Charitable Foundation NAthe Stephen Hargrave Trust NA
6 · The paper itself

Abstract

There is considerable interest in urine as a non-invasive liquid biopsy to detect prostate cancer (PCa). PCa-specific transcripts such as the

Indexed as

biomarkercancercell-sedimentextracellular vesiclesprostateurine

Identifiers

PMID36765747
PMCPMC9913640

What OpenQuestion holds

Textmetadata
LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.