Evidence map›Paper›PMID 36765740›Full record

ArticleCancers2023

Prevalence of Sarcopenia and Impact on Survival in Patients with Metastatic Gastroenteropancreatic Neuroendocrine Tumours.

Dominique S V M Clement, Monique E van Leerdam, Soraya de Jong, Martin O Weickert, John K Ramage, Margot E T Tesselaar, Rajaventhan Srirajaskanthan

Abstract read
In one paragraph

Article in Cancers, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Dominique S V M ClementKings Health Partners, ENETS Centre of Excellence, Institute of Liver Studies, King's College Hospital, London SE5 9RS, UK.ORCID 0000-0002-8116-962X
Monique E van LeerdamDepartment of Gastrointestinal Oncology, ENETS Centre of Excellence, Netherlands Cancer Institute, 1066 CX Amsterdam, The Netherlands.ORCID 0000-0002-5719-3208
Soraya de JongDepartment of Gastrointestinal Oncology, ENETS Centre of Excellence, Netherlands Cancer Institute, 1066 CX Amsterdam, The Netherlands.
Martin O WeickertThe ARDEN NET Centre, ENETS Centre of Excellence, University Hospitals Coventry & Warwckshire NHS Trust, Coventry CV2 2DX, UK.
John K RamageKings Health Partners, ENETS Centre of Excellence, Institute of Liver Studies, King's College Hospital, London SE5 9RS, UK.
Margot E T TesselaarDepartment of Gastrointestinal Oncology, ENETS Centre of Excellence, Netherlands Cancer Institute, 1066 CX Amsterdam, The Netherlands.
Rajaventhan SrirajaskanthanKings Health Partners, ENETS Centre of Excellence, Institute of Liver Studies, King's College Hospital, London SE5 9RS, UK.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Sarcopenia in patients with cancer is associated with adverse outcomes such as shorter survival. However, there exists little evidence regarding the prevalence of sarcopenia in patients with metastatic gastroenteropancreatic neuroendocrine tumours (GEP-NETs). Patients with a histologically confirmed newly diagnosed metastatic GEP-NET between 2006 and 2018, CT scan, and anthropometric data at diagnosis were included in this study. CT scans were analysed for the presence of sarcopenia and correlated with overall survival (OS). In total, 183 patients, 87 male (48%), with a median age of 62 years (IQR 52-68 years), were included. In 44 patients (24%), there was a pancreas NET, and in 136 patients, there was a small bowel NET (74%). Sarcopenia was present in 128 patients (69%) and unrelated to BMI (median 25.1). There were significant survival differences between patients with pancreatic and small bowel NETs at 86 vs. 141 months, respectively (

Indexed as

GEP-NETnutritional statussarcopeniasurvival

Identifiers

PMID36765740
PMCPMC9913815

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.