Evidence map›Paper›PMID 36765720›Full record

ArticleCancers2023

Apolonia Novillo, María Gaibar, Alicia Romero-Lorca, Diego Malón, Beatriz Antón, Amalia Moreno, Ana Fernández-Santander

Abstract read
In one paragraph

Article in Cancers, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Apolonia NovilloMedicine Faculty, Cellular Biology Section Department, Complutense University, 28040 Madrid, Spain.ORCID 0000-0003-0902-0991
María GaibarHuman Genetic Variability Group, Hospital La Paz Institute for Health Research-IdiPAZ (La Paz University Hospital-Universidad Autónoma de Madrid-Getafe University Hospital-Universidad Europea de Madrid), 28046 Madrid, Spain.
Alicia Romero-LorcaHuman Genetic Variability Group, Hospital La Paz Institute for Health Research-IdiPAZ (La Paz University Hospital-Universidad Autónoma de Madrid-Getafe University Hospital-Universidad Europea de Madrid), 28046 Madrid, Spain.ORCID 0000-0002-1920-034X
Diego MalónHuman Genetic Variability Group, Hospital La Paz Institute for Health Research-IdiPAZ (La Paz University Hospital-Universidad Autónoma de Madrid-Getafe University Hospital-Universidad Europea de Madrid), 28046 Madrid, Spain.
Beatriz AntónHuman Genetic Variability Group, Hospital La Paz Institute for Health Research-IdiPAZ (La Paz University Hospital-Universidad Autónoma de Madrid-Getafe University Hospital-Universidad Europea de Madrid), 28046 Madrid, Spain.
Amalia MorenoHuman Genetic Variability Group, Hospital La Paz Institute for Health Research-IdiPAZ (La Paz University Hospital-Universidad Autónoma de Madrid-Getafe University Hospital-Universidad Europea de Madrid), 28046 Madrid, Spain.
Ana Fernández-SantanderHuman Genetic Variability Group, Hospital La Paz Institute for Health Research-IdiPAZ (La Paz University Hospital-Universidad Autónoma de Madrid-Getafe University Hospital-Universidad Europea de Madrid), 28046 Madrid, Spain.ORCID 0000-0001-7545-1170

Funding

European University of Madrid 2020/UEM15, FGUE001804 and FGUE001805
6 · The paper itself

Abstract

The addition to chemotherapy of anti-HER2 drugs such as trastuzumab or pertuzumab has improved outcomes in HER2-positive breast cancer patients. However, resistance to these drugs in some patients remains a major concern. This study examines the possible association between the response to neoadjuvant anti-HER2 treatment in breast cancer patients and the presence of 28 SNPs in 17 genes involved in different cell processes (

Indexed as

anti-HER2 treatmentHER2 geneHER2-positive breast cancerMiller–Payne gradingpathological complete responseSNPs

Identifiers

PMID36765720
PMCPMC9913086

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.