Evidence map›Paper›PMID 36765702›Full record

ArticleCancers2023

Proteome-Wide Analysis Reveals TFEB Targets for Establishment of a Prognostic Signature to Predict Clinical Outcomes of Colorectal Cancer.

Zijia Huang, Sheng Zhu, Ziqin Han, Chen Li, Junze Liang, Yang Wang, Shuixing Zhang, Jing Zhang

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Cancers, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed.

  1. Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Zijia HuangDepartment of Radiology, The First Affiliated Hospital of Jinan University, Jinan University, Guangzhou 510613, China.
Sheng ZhuDepartment of Nuclear Medicine, Affiliated Hospital of Xiangnan University, Xiangnan University, Chenzhou 423000, China.
Ziqin HanDepartment of Radiology, The First Affiliated Hospital of Jinan University, Jinan University, Guangzhou 510613, China.
Chen LiDepartment of Radiology, The First Affiliated Hospital of Jinan University, Jinan University, Guangzhou 510613, China.
Junze LiangMOE Key Laboratory of Tumor Molecular Biology, Key Laboratory of Functional Protein Research of Guangdong Higher Education Institutes, Institute of Life and Health Engineering, College of Life Science and Technology, Jinan University, Guangzhou 510632, China.
Yang WangMOE Key Laboratory of Tumor Molecular Biology, Key Laboratory of Functional Protein Research of Guangdong Higher Education Institutes, Institute of Life and Health Engineering, College of Life Science and Technology, Jinan University, Guangzhou 510632, China.ORCID 0000-0001-6440-0204
Shuixing ZhangDepartment of Radiology, The First Affiliated Hospital of Jinan University, Jinan University, Guangzhou 510613, China.
Jing ZhangDepartment of Radiology, The First Affiliated Hospital of Jinan University, Jinan University, Guangzhou 510613, China.ORCID 0000-0002-2488-5021

Funding

Basic Research Funds for Central universities of Jinan University 21622110Clinical Medical Technology Innovation Guidance Project of Hunan Province 22020SK52202National Natural Science Foundation of China 82227802
6 · The paper itself

Abstract

Dephosphorylation of transcription factor EB (TFEB) at Ser142 and Ser138 determines its nuclear localization and transcriptional activity. The link between TFEB-associated genes and colorectal cancer (CRC) progression and prognosis remains unclear. To systematically identify the targets of TFEB, we performed data-independent acquisition (DIA)-based quantitative proteomics to compare global protein changes in wild-type (WT) DLD1 cells and TFEB

Indexed as

colorectal cancerDIA-based proteomicsTFEBvesicular endocytic trafficking

Identifiers

PMID36765702
PMCPMC9913156

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.