Evidence map›Paper›PMID 36765687›Full record

ArticleCancers2023

Is Reflex Germline

Robert D Morgan, George J Burghel, Nicola Flaum, Michael Bulman, Philip Smith, Andrew R Clamp, Jurjees Hasan, Claire L Mitchell, Zena Salih, Emma R Woodward and 6 more

Open access · goldAbstract read
In one paragraph

Article in Cancers, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.5field-weighted citation impact, top 29% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 2 citations in OpenAlex.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

16 authors at 2 institutions in 1 country.

Robert D MorganDepartment of Medical Oncology, The Christie NHS Foundation Trust, Wilmslow Road, Manchester M20 4BX, UK.ORCID 0000-0003-0612-0954
George J BurghelManchester Centre for Genomic Medicine, North West Genomic Laboratory Hub, Saint Mary's Hospital, Oxford Road, Manchester M13 9WL, UK.ORCID 0000-0001-9360-8194
Nicola FlaumDepartment of Medical Oncology, The Christie NHS Foundation Trust, Wilmslow Road, Manchester M20 4BX, UK.ORCID 0000-0001-8900-0645
Michael BulmanManchester Centre for Genomic Medicine, North West Genomic Laboratory Hub, Saint Mary's Hospital, Oxford Road, Manchester M13 9WL, UK.
Philip SmithManchester Centre for Genomic Medicine, North West Genomic Laboratory Hub, Saint Mary's Hospital, Oxford Road, Manchester M13 9WL, UK.
Andrew R ClampDepartment of Medical Oncology, The Christie NHS Foundation Trust, Wilmslow Road, Manchester M20 4BX, UK.
Jurjees HasanDepartment of Medical Oncology, The Christie NHS Foundation Trust, Wilmslow Road, Manchester M20 4BX, UK.
Claire L MitchellDepartment of Medical Oncology, The Christie NHS Foundation Trust, Wilmslow Road, Manchester M20 4BX, UK.
Zena SalihDepartment of Medical Oncology, The Christie NHS Foundation Trust, Wilmslow Road, Manchester M20 4BX, UK.
Emma R WoodwardDivision of Evolution and Genomic Sciences, Faculty of Biology, Medicine and Health, University of Manchester, Manchester M13 9PL, UK.
Fiona LallooDepartment of Clinical Genetics, Saint Mary's Hospital, Oxford Road, Manchester M13 9WL, UK.
Emma J CrosbieDivision of Cancer Sciences, Faculty of Biology, Medicine and Health, University of Manchester, Manchester M13 9PL, UK.ORCID 0000-0003-0284-8630
Richard J EdmondsonDivision of Cancer Sciences, Faculty of Biology, Medicine and Health, University of Manchester, Manchester M13 9PL, UK.ORCID 0000-0003-2553-4423
Helene SchlechtManchester Centre for Genomic Medicine, North West Genomic Laboratory Hub, Saint Mary's Hospital, Oxford Road, Manchester M13 9WL, UK.
Gordon C JaysonDepartment of Medical Oncology, The Christie NHS Foundation Trust, Wilmslow Road, Manchester M20 4BX, UK.
D Gareth R EvansManchester Centre for Genomic Medicine, North West Genomic Laboratory Hub, Saint Mary's Hospital, Oxford Road, Manchester M13 9WL, UK.ORCID 0000-0002-8482-5784
University of Manchester · GBThe Christie NHS Foundation Trust · GB

Funding

Cancer Research UK 29832
6 · The paper itself

Abstract

Women diagnosed with non-mucinous high-grade epithelial ovarian cancer (EOC) in England are often reflex-tested for germline and tumour

Indexed as

BRCA1BRCA2epithelial ovarian cancergermlinesomatic

Identifiers

PMID36765687
PMCPMC9913244
OpenAlexW4317933119

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.