Evidence map›Paper›PMID 36765681›Full record

ArticleCancers2023

Prognostic Impact of Sarcopenia's Occurrence during Radiotherapy in Oropharyngeal Cancer Patients.

Luca Bergamaschi, Giulia Marvaso, Mattia Zaffaroni, Maria Giulia Vincini, Oriana D'Ecclesiis, Stefania Volpe, Annamaria Ferrari, Stefano Filippo Zorzi, Maria Cossu Rocca, Annarita Sabbatini and 9 more

Abstract read
In one paragraph

Article in Cancers, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Trial
  3. Trial
  4. Article
  5. Physical activity in people affected by head and neck cancers: gender-specific barriers and preferences-ORLAPA survey results.Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer · 2025
    Article
  6. Metabolic Implications of Childhood Cancer.Current pediatrics reports · 2025
    Article
  7. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

19 authors.

Luca BergamaschiDivision of Radiation Oncology, European Institute of Oncology IRCCS, 20141 Milan, Italy.
Giulia MarvasoDivision of Radiation Oncology, European Institute of Oncology IRCCS, 20141 Milan, Italy.ORCID 0000-0002-5339-8038
Mattia ZaffaroniDivision of Radiation Oncology, European Institute of Oncology IRCCS, 20141 Milan, Italy.ORCID 0000-0003-4655-4634
Maria Giulia VinciniDivision of Radiation Oncology, European Institute of Oncology IRCCS, 20141 Milan, Italy.ORCID 0000-0001-7830-3149
Oriana D'EcclesiisDepartment of Experimental Oncology, European Institute of Oncology, IRCCS, 20141 Milan, Italy.
Stefania VolpeDivision of Radiation Oncology, European Institute of Oncology IRCCS, 20141 Milan, Italy.
Annamaria FerrariDivision of Radiation Oncology, European Institute of Oncology IRCCS, 20141 Milan, Italy.
Stefano Filippo ZorziDepartment of Otolaryngology and Head and Neck Surgery, European Institute of Oncology IRCCS, 20141 Milan, Italy.
Maria Cossu RoccaDepartment of Medical Oncology, Urogenital and Head and Neck Tumors Medical Treatment, European Institute of Oncology IRCCS, 20141 Milan, Italy.ORCID 0000-0002-5780-3774
Annarita SabbatiniDietetic and Clinical Nutrition Unit, European Institute of Oncology IRCSS, 20141 Milan, Italy.
Giulia CannilloDietetic and Clinical Nutrition Unit, European Institute of Oncology IRCSS, 20141 Milan, Italy.
Emanuela ZagalloDietetic and Clinical Nutrition Unit, European Institute of Oncology IRCSS, 20141 Milan, Italy.
Anna StarzyńskaDepartment of Oral Surgery, Medical University of Gdańsk, 80210 Gdańsk, Poland.ORCID 0000-0001-6900-0429
Mohssen AnsarinDepartment of Otolaryngology and Head and Neck Surgery, European Institute of Oncology IRCCS, 20141 Milan, Italy.
Federica CattaniUnit of Medical Physics, European Institute of Oncology, IRCCS, 20141 Milan, Italy.
Sara GandiniDepartment of Experimental Oncology, European Institute of Oncology, IRCCS, 20141 Milan, Italy.ORCID 0000-0002-1348-4548
Roberto OrecchiaUnit of Medical Physics, European Institute of Oncology, IRCCS, 20141 Milan, Italy.
Daniela AlterioDivision of Radiation Oncology, European Institute of Oncology IRCCS, 20141 Milan, Italy.
Barbara Alicja Jereczek-FossaDivision of Radiation Oncology, European Institute of Oncology IRCCS, 20141 Milan, Italy.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The current study aims to profile sarcopenic condition (both at baseline and developed during treatment) in oropharyngeal carcinoma (OPC) patients treated with curative radiotherapy (RT) +/- chemotherapy and to evaluate its impact on oncological outcomes and toxicity. A total of 116 patients were included in this retrospective single-center study. Sarcopenia assessment at baseline and at 50 Gy re-evaluation CT was obtained from two different methodologies: (i) the L3-skeletal muscle index (SMI) derived from the contouring of the cross-sectional area (CSA) of the masticatory muscles (CSA-MM); and (ii) the paravertebral and sternocleidomastoid muscles at the level of the third cervical vertebra (CSA-C3). Based on L3-SMI from CSA-MM, developing sarcopenic condition during RT (on-RT sarcopenia) was associated with worse progression-free survival (PFS) (

Indexed as

HPVnutritional supportoncological outcomesoropharyngeal carcinomasarcopenia

Identifiers

PMID36765681
PMCPMC9913355

What OpenQuestion holds

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Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.