ArticleCancers2023
Performance of Node-RADS Scoring System for a Standardized Assessment of Regional Lymph Nodes in Bladder Cancer Patients.
Article in Cancers, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 28 papers, 2 of them syntheses that pooled it.
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Who cites it
28 citing papers in PubMed, 2 syntheses or guidelines pooled it.
- Diagnostic accuracy of node-RADS for the detection of lymph node invasion: a systematic review and meta-analysis.European radiology · 2025Pooled it
- Node-RADS: a systematic review and meta-analysis of diagnostic performance, category-wise malignancy rates, and inter-observer reliability.European radiology · 2025Pooled it
- Assessment of inter-reader agreement and diagnostic performance of Node-RADS in colon cancer.Insights into imaging · 2026Article
- Prognostic and Diagnostic Value of Node-RADS for Non-Small Cell Lung Cancer Following Neoadjuvant Therapy: A Multicenter Cohort Study.Diagnostics (Basel, Switzerland) · 2026Article
- Node-RADS in cervical cancer: a multi-reader agreement and diagnostic performance study.Cancer imaging : the official publication of the International Cancer Imaging Society · 2026Article
- A head-to-head comparison of MRI and CT using Node-RADS for rectal cancer lymph nodes: Observer agreement and diagnostic performance.European journal of radiology open · 2026Article
- Multireader diagnostic performance of MRI-based Node-RADS for pelvic lymph node metastasis in endometrial carcinoma.European radiology · 2026Article
- Prognostic value of Node-RADS scoring in stage IIICr cervical cancer: development and validation of novel nomograms.Insights into imaging · 2026Article
- Diagnostic performance of Node-RADS on MRI for a standardized assessment of lymph node metastasis in ovarian cancer.Abdominal radiology (New York) · 2026Article
- An improved diagnostic criterion based on Node-RADS MRI score for lymph node metastasis in papillary thyroid carcinoma.Quantitative imaging in medicine and surgery · 2026Article
- Predictive value of node-RADS scoring system for axillary lymph node metastasis in breast cancer.BMC medical imaging · 2026Article
- Development and validation of MRI-based models to predict lymph node metastasis in bladder cancer: a multi-center study.Cancer imaging : the official publication of the International Cancer Imaging Society · 2026Article
- The diagnostic efficacy of venous-phase spectral CT combined with Node-RADS for differentiating enlarged lymph nodes in common solid tumors: a preliminary exploratory study.Frontiers in oncology · 2026Article
- Added value of pretreatment CT-based Node-RADS score for predicting survival outcome of locally advanced gastric cancer: compared with clinical N stage.BMC cancer · 2025Article
- Node Reporting and Data System 1.0 (Node-RADS) for the Assessment of Oncological Patients' Lymph Nodes in Clinical Imaging.Journal of clinical medicine · 2025Review
- Diagnostic accuracy and reliability of CT-based Node-RADS for colon cancer.Abdominal radiology (New York) · 2025Article
- Performance of MRI for standardized lymph nodes assessment in breast cancer: are we ready for Node-RADS?European radiology · 2024Article
- Stratifying the Risk of Disease Progression among Surgically Treated Muscle-Invasive Bladder Cancer Eligible for Adjuvant Nivolumab.Journal of clinical medicine · 2024Article
- The performance of the node reporting and data system 1.0 (Node-RADS) and DWI-MRI in staging patients with cervical carcinoma according to the new FIGO classification (2018).La Radiologia medica · 2024Article
- Diagnostic performance of Node Reporting and Data System (Node-RADS) for assessing mesorectal lymph node in rectal cancer by CT.BMC cancer · 2024Article
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17 authors.
Funding
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Abstract
backgroundCurrent cross-sectional imaging modalities exhibit heterogenous diagnostic performances for the detection of a lymph node invasion (LNI) in bladder cancer (BCa) patients. Recently, the Node-RADS score was introduced to provide a standardized comprehensive evaluation of LNI, based on a five-item Likert scale accounting for both size and configuration criteria. In the current study, we hypothesized that the Node-RADS score accurately predicts the LNI and tested its diagnostic performance.
methodsWe retrospectively reviewed BCa patients treated with radical cystectomy (RC) and bilateral extended pelvic lymph node dissection, from January 2019 to June 2022. Patients receiving preoperative systemic chemotherapy were excluded. A logistic regression analysis tested the correlation between the Node-RADS score and LNI both at patient and lymph-node level. The ROC curves and the AUC depicted the overall diagnostic performance. In addition, the sensitivity, specificity, positive predictive value (PPV), and negative predictive value (NPV) were calculated for different cut-off values (>1, >2, >3, >4).
resultsOverall, data from 49 patients were collected. Node-RADS assigned on CT scans images, was found to independently predict the LNI after an adjusted multivariable regression analysis, both at the patient (OR 3.36, 95%CI 1.68-9.40,
conclusionsThe current study lays the foundation for the introduction of Node-RADS for the regional lymph-node evaluation in BCa patients. Interestingly, the Node-RADS score exhibited a moderate-to-high overall accuracy for the identification of LNI, with the possibility of setting different cut-off values according to specific clinical scenarios. However, these results need to be validated on larger cohorts before drawing definitive conclusions.
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