Evidence map›Paper›PMID 36765459›Full record

ArticleMolecular pain

Resolvin D1 attenuates mechanical allodynia after burn injury: Involvement of spinal glia, p38 mitogen-activated protein kinase, and brain-derived neurotrophic factor/tropomyosin-related kinase B signaling.

Xiaona Zhao, Xinxin Li, Huiling Guo, Panmei Liu, Minyu Ma, Yanping Wang

Open access · goldAbstract read
In one paragraph

Article in Molecular pain. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
1.8field-weighted citation impact, top 16% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 10 citations in OpenAlex.

  1. Review
  2. Article
  3. Pathophysiology and management of burn injury-induced pain.Burns open : an international open access journal for burn injuries · 2025
    Article
  4. Article
  5. Resolvin D2 restores monocyte anisocytosis and mediates a shift toward classical monocytes ex vivo in blood samples from patients after major burns.FASEB journal : official publication of the Federation of American Societies for Experimental Biology · 2025
    Article
  6. Review
  7. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 1 institution in 1 country.

Xiaona ZhaoDepartment of Anesthesiology, Pain and Perioperative Medicine, 191599The First Affiliated Hospital of Zhengzhou University, Zhengzhou, China.ORCID 0000-0001-6861-148X
Xinxin LiDepartment of Anesthesiology, Pain and Perioperative Medicine, 191599The First Affiliated Hospital of Zhengzhou University, Zhengzhou, China.
Huiling GuoDepartment of Anesthesiology, Pain and Perioperative Medicine, 191599The First Affiliated Hospital of Zhengzhou University, Zhengzhou, China.
Panmei LiuDepartment of Anesthesiology, Pain and Perioperative Medicine, 191599The First Affiliated Hospital of Zhengzhou University, Zhengzhou, China.
Minyu MaDepartment of Anesthesiology, Pain and Perioperative Medicine, 191599The First Affiliated Hospital of Zhengzhou University, Zhengzhou, China.
Yanping WangDepartment of Anesthesiology, Pain and Perioperative Medicine, 191599The First Affiliated Hospital of Zhengzhou University, Zhengzhou, China.
First Affiliated Hospital of Zhengzhou University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Resolvin D1 (RvD1) suppresses inflammatory, postoperative, and neuropathic pain. The present study assessed the roles and mechanisms of RvD1 in mechanical allodynia after burn injury. A rat model of burn injury was established for analyses, and RvD1 was injected intraperitoneally. Pain behavior and the expression levels of spinal dorsal horn Iba-1 (microglia marker), GFAP (astrocyte marker),

Indexed as

BurnsHyperalgesiaAnimalsBrain-Derived Neurotrophic FactorDocosahexaenoic AcidsMicrogliap38 Mitogen-Activated Protein KinasesRatsRats, Sprague-DawleySpinal Cord Dorsal HornTropomyosinBrain-Derived Neurotrophic FactorDocosahexaenoic Acidsp38 Mitogen-Activated Protein Kinasesresolvin D1TropomyosinastrocytesBDNF/TrkBmechanical allodynia after burn injurymicrogliap38 MAPKRvD1

Identifiers

PMID36765459
PMCPMC9986910
OpenAlexW4320032528

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.