ArticleNPJ digital medicine2023
Evidence from ClinicalTrials.gov on the growth of Digital Health Technologies in neurology trials.
Article in NPJ digital medicine, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 62 papers, 2 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
62 citing papers in PubMed, 2 syntheses or guidelines pooled it.
- Applications of digital health technologies and artificial intelligence algorithms in COPD: systematic review.BMC medical informatics and decision making · 2025Pooled it
- Economic Evaluation Associated With Clinical-Grade Mobile App-Based Digital Therapeutic Interventions: Systematic Review.Journal of medical Internet research · 2023Pooled it
- Digital signatures of fatigue and wearing-off symptoms in patients with multiple sclerosis under natalizumab.Neurotherapeutics : the journal of the American Society for Experimental NeuroTherapeutics · 2026Article
- Delivering high-quality multiple sclerosis care in Germany: challenges and regional models.Neurological research and practice · 2026Review
- Rethinking EDSS-based ambulation assessment in multiple sclerosis using continuous variable monitoring.Neurological research and practice · 2026Article
- The Impact of Sunlight and Artificial Light at Night on Sleep Stages: Evidence From a 7-Day Sensor-Based Observational Study.JMIR mHealth and uHealth · 2026Observational
- Body placement of inertial measurement units differentially affects physical activity assessment accuracy in drug-naïve Parkinson's disease.Scientific reports · 2026Article
- The include network: Advancing cross-linguistic equity in brain health research.Alzheimer's & dementia : the journal of the Alzheimer's Association · 2026Article
- MS360°: a conceptual digital-first, data-driven hybrid care framework for personalised multiple sclerosis management.NPJ digital medicine · 2026Review
- Digital Health Literacy and Health Technology Readiness Among People With Epilepsy or Multiple Sclerosis: Cross-Sectional Study.JMIR human factors · 2026Article
- The research progress of wearable digital health technologies in epilepsy management.Acta epileptologica · 2026Review
- The landscape of dementia research, diagnosis, treatment, and care in Latin America.Alzheimer's & dementia : the journal of the Alzheimer's Association · 2026Review
- Artificial intelligence for clinical trial design, conduct, and analysis: a narrative review.ESMO real world data and digital oncology · 2026Review
- Stride-level measurement of gait as an early sensitive marker of disability progression in ambulatory patients with multiple sclerosis.EClinicalMedicine · 2026Article
- Case-Based Lessons on Remote Patient Monitoring in Neurology Using Consumer-Grade Wearables.Journal of central nervous system disease · 2026Article
- Speech and language outcome measures in clinical trials of Alzheimer's and Parkinson's diseases.Expert review of neurotherapeutics · 2026Review
- Wearable Monitoring Captures Sleep Disturbances in Patients With Chronic Inflammatory Demyelinating Polyneuropathy.Journal of the peripheral nervous system : JPNS · 2025Observational
- Speech-based digital cognitive assessments for detection of mild cognitive impairment: Validation against paper-based neurocognitive assessment scores.Journal of Alzheimer's disease : JAD · 2025Article
- Regulatory Interactions and Learnings-RADIAL the Trials@Home Proof-of-Concept Trial on Decentralization.Clinical pharmacology and therapeutics · 2025Article
- Digital Activity Markers in Chronic Inflammatory Demyelinating Polyneuropathy.Annals of clinical and translational neurology · 2025Observational
2 more citing papers are in PubMed but not listed here.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
5 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Digital Health Technologies (DHTs) such as connected sensors offer particular promise for improving data collection and patient empowerment in neurology research and care. This study analyzed the recent evolution of the use of DHTs in trials registered on ClinicalTrials.gov for four chronic neurological disorders: epilepsy, multiple sclerosis, Alzheimer's, and Parkinson's disease. We document growth in the collection of both more established digital measures (e.g., motor function) and more novel digital measures (e.g., speech) over recent years, highlighting contexts of use and key trends.
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.