ArticleScientific reports2023
Genetic predisposition to smoking in relation to the risk of frailty in ageing.
Article in Scientific reports, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.
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Who cites it
11 citing papers in PubMed.
- Trends and lifestyle contributions to frailty in US adults aged 50 and older: analysis of health and retirement study data (2004-2020).BMC public health · 2026Article
- Evaluating the association of physical frailty with cognitive impairment: a clinical perspective in older adults of Bangladesh.BMC geriatrics · 2026Article
- Frailty and Cardiovascular Risk.European cardiology · 2026Review
- Early-life exposure to tobacco smoke increase risk of frailty in adulthood: evidence from a large prospective cohort study.Journal of translational medicine · 2025Article
- Article
- Long-term smoking contributes to aging frailty and inflammatory response.Biomolecules & biomedicine · 2025Article
- Lifestyle, environment and other major determinants of frailty in older adults: a population-based study from the UK Biobank.Biogerontology · 2025Article
- Association of frailty with non-laboratory based cardiovascular disease risk score among older adults and elderly population: insights from longitudinal aging study in India (LASI-1st wave).BMC public health · 2025Article
- Prevalence of physical frailty and its associated factors among elderly patients undergoing hepatobiliary pancreatic surgery in China.Global health & medicine · 2024Article
- The Association Between an Electronic Health Record (EHR)-Embedded Frailty Index and Patient-Reported Outcomes Among Patients with Metastatic Non-Small-Cell Lung Cancer on Immunotherapy: A Brief Report.The American journal of hospice & palliative care · 2024Article
- Pre-frailty after blood or marrow transplantation and the risk of subsequent mortality.Leukemia · 2024Article
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Authors and funding
8 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Frailty causes emerging global health burden due to its high prevalence and mortality. In this study, we used Mendelian randomization (MR) approach to examine the potential causal relationship between smoking and frailty in ageing. Using inverse-variance weighted (IVW) method, genetically predicted smoking initiation was associated with an increased risk of frailty in ageing (odd ratio (OR) 1.23, 95% confidence interval (CI) 1.19-1.27, P = 3.21 × 10
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Registered trials
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