Evidence map›Paper›PMID 36765102›Full record

ReviewISME communications2021

iVirus 2.0: Cyberinfrastructure-supported tools and data to power DNA virus ecology.

Benjamin Bolduc, Olivier Zablocki, Jiarong Guo, Ahmed A Zayed, Dean Vik, Paramvir Dehal, Elisha M Wood-Charlson, Adam Arkin, Nirav Merchant, Jennifer Pett-Ridge and 3 more

Abstract readReview
In one paragraph

Review in ISME communications, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

13 citing papers in PubMed.

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  5. Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors.

Benjamin BolducDepartment of Microbiology, The Ohio State University, Columbus, OH, USA.ORCID http://orcid.org/0000-0003-2420-0755
Olivier ZablockiDepartment of Microbiology, The Ohio State University, Columbus, OH, USA.ORCID http://orcid.org/0000-0001-7561-1373
Jiarong GuoDepartment of Microbiology, The Ohio State University, Columbus, OH, USA.
Ahmed A ZayedDepartment of Microbiology, The Ohio State University, Columbus, OH, USA.
Dean VikDepartment of Microbiology, The Ohio State University, Columbus, OH, USA.
Paramvir DehalEnvironmental Genomics and Systems Biology Division, E.O. Lawrence Berkeley National Laboratory, Berkeley, CA, USA.
Elisha M Wood-CharlsonEnvironmental Genomics and Systems Biology Division, E.O. Lawrence Berkeley National Laboratory, Berkeley, CA, USA.ORCID http://orcid.org/0000-0001-9557-7715
Adam ArkinEnvironmental Genomics and Systems Biology Division, E.O. Lawrence Berkeley National Laboratory, Berkeley, CA, USA.
Nirav MerchantThe University of Arizona, Tucson, AZ, USA.
Jennifer Pett-RidgePhysical and Life Sciences Directorate, Lawrence Livermore National Laboratory, Livermore, CA, USA.ORCID http://orcid.org/0000-0002-4439-2398
Simon RouxDOE Joint Genome Institute, Lawrence Berkeley National Laboratory, Berkeley, CA, USA.
Matthew VaughnTexas Advanced Computing Center, The University of Texas at Austin, Austin, TX, USA.ORCID http://orcid.org/0000-0002-1384-4283
Matthew B SullivanDepartment of Microbiology, The Ohio State University, Columbus, OH, USA. mbsulli@gmail.com.ORCID http://orcid.org/0000-0001-8398-8234

Funding

DOE | Office of Science (SC) DE-AC02-05CH11231DOE | Office of Science (SC) DE-AC52-07NA27344DOE | Office of Science (SC) SCW1632DOE | Office of Science (SC) SCW1656National Science Foundation (NSF) 1663578NSF | BIO | Division of Biological Infrastructure (DBI) DBI-1743442
6 · The paper itself

Abstract

Microbes drive myriad ecosystem processes, but under strong influence from viruses. Because studying viruses in complex systems requires different tools than those for microbes, they remain underexplored. To combat this, we previously aggregated double-stranded DNA (dsDNA) virus analysis capabilities and resources into 'iVirus' on the CyVerse collaborative cyberinfrastructure. Here we substantially expand iVirus's functionality and accessibility, to iVirus 2.0, as follows. First, core iVirus apps were integrated into the Department of Energy's Systems Biology KnowledgeBase (KBase) to provide an additional analytical platform. Second, at CyVerse, 20 software tools (apps) were upgraded or added as new tools and capabilities. Third, nearly 20-fold more sequence reads were aggregated to capture new data and environments. Finally, documentation, as "live" protocols, was updated to maximize user interaction with and contribution to infrastructure development. Together, iVirus 2.0 serves as a uniquely central and accessible analytical platform for studying how viruses, particularly dsDNA viruses, impact diverse microbial ecosystems.

Identifiers

PMID36765102
PMCPMC9723767

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.