ArticleScientific reports2023
Pathogens associated with hospitalization due to acute lower respiratory tract infections in children in rural Ghana: a case-control study.
Article in Scientific reports, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers, 1 of them a synthesis that pooled it.
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Who cites it
8 citing papers in PubMed, 1 synthesis or guideline pooled it, 9 citations in OpenAlex.
- Pneumonia in Ghana: prevalence, mortality and antimicrobial resistance-a systematic review and meta-analysis.International health · 2026Pooled it
- Prevalence, associated factors and treatment prescriptions for community-acquired pneumonia: a cross-sectional study at the largest children's hospital in the Ashanti Region, Ghana.BMC infectious diseases · 2026Article
- Spatiotemporal modeling of Under-Five Pneumonia (U-5P) risk in Ghana using Integrated Nested Laplace Approximations, 2018-2022.BMC public health · 2026Article
- The prevalence and role of human respiratory syncytial virus in pediatric respiratory tract infections: a systematic review and meta-analysis of global data.EClinicalMedicine · 2026Article
- Analysis of bacterial pathogen spectrum and epidemiological characteristics of pediatric lower respiratory tract infections: a large sample study based on bronchoalveolar lavage.BMC infectious diseases · 2025Article
- Prevalence of common respiratory viruses in children: insights from post-pandemic surveillance.BMC infectious diseases · 2025Article
- Co-infections of SARS-CoV-2 with respiratory syncytial virus and human influenza A in patients with symptoms of COVID-19 in Ghana: A retrospective study.New microbes and new infections · 2024Article
- Viral Acute Lower Respiratory Tract Infections (ALRI) in Rural Bangladeshi Children Prior to the COVID-19 Pandemic.Influenza and other respiratory viruses · 2024Article
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Authors and funding
15 authors at 8 institutions in 4 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Respiratory infections are one of the most common causes of death among children under the age of five years. Data on prevalence and relevance of specific organisms in African children are still lacking. This case-control-study investigated prevalence and relevance of specific organisms in Ghanaian children admitted to hospital with symptoms of lower respiratory tract infection (LRTI). Pharyngeal swabs were taken and tested by PCR for 19 respiratory isolates. Adjusted odds ratios (aORs) were calculated to estimate associations between isolates and admission with LRTI. Population attributable fractions (PAFs) were calculated to assess the proportion of LRTI cases due to a particular pathogen. The study included 327 cases and 562 controls. We found associations between detection and admission for LRTI for influenza (aOR 98.6; 95% confidence interval (CI) 20.0-1789.6), respiratory syncytial virus (aOR 40.2; 95% CI 7.2-758.6), H. influenzae (aOR 4.1; 95% CI 2.2-7.9) and S. pneumoniae (aOR 2.4; 95% CI 1.7-3.4). PAFs ≥ 10% were observed for S. pneumoniae (30%; 95% CI 26-42), H. influenzae (10%; 95% CI 2-19) and influenza (10%; 95% CI 2-18). This study highlights the need for heightened surveillance and development of effective vaccines for respiratory pathogens other than SARS-CoV-2 in the future.
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