Evidence map›Paper›PMID 36765054›Full record

ArticleNature communications2023

A conserved tooth resorption mechanism in modern and fossil snakes.

A R H LeBlanc, A Palci, N Anthwal, A S Tucker, R Araújo, M F C Pereira, M W Caldwell

Open access · goldAbstract read
In one paragraph

Article in Nature communications, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
2.3field-weighted citation impact, top 13% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 15 citations in OpenAlex.

  1. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 4 institutions in 4 countries.

A R H LeBlancDepartment of Biological Sciences, University of Alberta, Edmonton, AB, Canada. aaron.leblanc@kcl.ac.uk.ORCID 0000-0002-2497-1296
A PalciSchool of Biological Sciences, University of Adelaide, Adelaide, SA, Australia.
N AnthwalCentre for Craniofacial & Regenerative Biology, King's College London, London, United Kingdom.ORCID 0000-0002-4104-7839
A S TuckerCentre for Craniofacial & Regenerative Biology, King's College London, London, United Kingdom.ORCID 0000-0001-8871-6094
R AraújoInstituto de Plasmas e Fusão Nuclear, Instituto Superior Técnico, Universidade de Lisboa, Lisbon, Portugal.ORCID 0000-0001-5058-2983
M F C PereiraCERENA, Instituto Superior Técnico, Universidade de Lisboa, Lisbon, Portugal.
M W CaldwellDepartment of Biological Sciences, University of Alberta, Edmonton, AB, Canada.
King's College London · GBUniversity of Alberta · CAUniversity of Lisbon · PTSouth Australian Museum · AU

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Whether snakes evolved their elongated, limbless bodies or their specialized skulls and teeth first is a central question in squamate evolution. Identifying features shared between extant and fossil snakes is therefore key to unraveling the early evolution of this iconic reptile group. One promising candidate is their unusual mode of tooth replacement, whereby teeth are replaced without signs of external tooth resorption. We reveal through histological analysis that the lack of resorption pits in snakes is due to the unusual action of odontoclasts, which resorb dentine from within the pulp of the tooth. Internal tooth resorption is widespread in extant snakes, differs from replacement in other reptiles, and is even detectable via non-destructive μCT scanning, providing a method for identifying fossil snakes. We then detected internal tooth resorption in the fossil snake Yurlunggur, and one of the oldest snake fossils, Portugalophis, suggesting that it is one of the earliest innovations in Pan-Serpentes, likely preceding limb loss.

Indexed as

ToothTooth ResorptionAnimalsBiological EvolutionFossilsPhylogenyReptilesSnakes

Identifiers

PMID36765054
PMCPMC9918488
OpenAlexW4319984359

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.