Evidence map›Paper›PMID 36764483›Full record

Trial reportJournal of the Academy of Consultation-Liaison Psychiatry

Effectiveness of Collaborative Care and Colocated Specialty Care for Bipolar Disorder in Primary Care: A Secondary Analysis of a Randomized Clinical Trial.

Joseph M Cerimele, Brittany E Blanchard, Morgan Johnson, Joan Russo, Amy M Bauer, Richard C Veith, Jürgen Unützer, John C Fortney

Open access · greenAbstract readRandomized Controlled Trial
In one paragraph

Trial report in Journal of the Academy of Consultation-Liaison Psychiatry. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
1.6field-weighted citation impact, top 19% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 7 citations in OpenAlex.

  1. Trial
  2. Article
  3. Article
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 1 institution in 1 country.

Joseph M CerimeleDepartment of Psychiatry & Behavioral Sciences, University of Washington School of Medicine, Seattle, WA. Electronic address: cerimele@uw.edu.
Brittany E BlanchardDepartment of Psychiatry & Behavioral Sciences, University of Washington School of Medicine, Seattle, WA.
Morgan JohnsonDepartment of Psychiatry & Behavioral Sciences, University of Washington School of Medicine, Seattle, WA.
Joan RussoDepartment of Psychiatry & Behavioral Sciences, University of Washington School of Medicine, Seattle, WA.
Amy M BauerDepartment of Psychiatry & Behavioral Sciences, University of Washington School of Medicine, Seattle, WA.
Richard C VeithDepartment of Psychiatry & Behavioral Sciences, University of Washington School of Medicine, Seattle, WA.
Jürgen UnützerDepartment of Psychiatry & Behavioral Sciences, University of Washington School of Medicine, Seattle, WA.
John C FortneyDepartment of Psychiatry & Behavioral Sciences, University of Washington School of Medicine, Seattle, WA; Department of Veterans Affairs, HSR&D Center of Innovation for Veteran-Centered and Value-Driven Care, VA Puget Sound Health Care System, Seattle, WA.
University of Washington · US

Funding

NCCIH Supplement to NCATS/CTSA Program for KL2 Scholars - M. SoddersKL2TR002317 · NCATS · UNIVERSITY OF WASHINGTON · PI Christy Michelle McKinney · 2017 to 2026
$14.5M
NCATS NIH HHS KL2 TR002317
6 · The paper itself

Abstract

backgroundIndividuals with bipolar disorder commonly present for treatment in primary care settings. Collaborative care and colocated specialty care models can improve quality of care and outcomes, though it is unknown which model is more effective.

objectiveTo compare 12-month treatment outcomes for primary care patients with bipolar disorder randomized to treatment with collaborative care or colocated specialty care.

methodsWe conducted a secondary analysis of 191 patients diagnosed with bipolar disorder treated for 12 months during a comparative effectiveness trial in 12 Federally Qualified Health Centers in three states. Characteristics and outcomes were assessed at enrollment and 12 months. The primary outcome was mental health quality of life scores (Veterans RAND 12-Item Health Survey Mental Health Component Summary), and secondary outcomes included depression and anxiety symptom scores, euthymic mood state, and recovery. T-tests and multiple linear and logistic regression models were used.

resultsAmong participants (mean age: 40 years; 73% women), the Veterans RAND 12-Item Health Survey Mental Health Component Summary increased in both arms over 12 months (baseline: collaborative care 21.99, SD 10.78; colocated specialty 24.15, SD 12.05; 12-month collaborative care 30.63, SD 13.33; colocated specialty 34.16, SD 12.65). The mean Mental Health Component Summary change did not differ by arm (collaborative care: MΔ = 9.09; colocated specialty: MΔ = 10.73; t = -0.67, P = 0.50). Secondary outcomes also improved at 12 months compared to baseline measured by the Hopkins Symptoms Checklist (MΔ = -0.75; SD = 0.85), Generalized Anxiety Disorder-7 (MΔ = -3.92; SD = 6.48), and Recovery Assessment Scale (MΔ = 0.37; SD = 0.65) and did not differ significantly by arm. The proportion of participants with euthymic mood state increased from 11% to 25% with no statistically significant difference by arm.

conclusionsThe effectiveness of collaborative care and that of colocated specialty care were similar. Both were associated with substantial improvements in mental health quality of life and symptom reduction.

Indexed as

Bipolar DisorderAdultAnxiety DisordersFemaleHumansMaleMental HealthPrimary Health CareQuality of Lifebipolar disordercollaborative careintegrated careprimary care

Identifiers

PMID36764483
PMCPMC10688610
OpenAlexW4319764597

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.