ArticleBiophysical journal1987
Magnetic particle motions within living cells. Measurement of cytoplasmic viscosity and motile activity.
Article in Biophysical journal, 1987. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 46 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
46 citing papers in PubMed, 183 citations in OpenAlex.
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- Diffusion and Viscosity in Mixed Protein Solutions.The journal of physical chemistry. B · 2024Article
- A Simulation of the Mechanical Testing of the Cell Membrane and Cytoskeleton.Micromachines · 2024Article
- The nonlinear motion of cells subject to external forces.Soft matter · 2022Article
- Mechanical Characterization and Modelling of Subcellular Components of Oocytes.Micromachines · 2022Article
- Microtubule assembly and disassembly dynamics model: Exploring dynamic instability and identifying features of Microtubules' Growth, Catastrophe, Shortening, and Rescue.Computational and structural biotechnology journal · 2022Article
- Recent Advancements in Hyperthermia-Driven Controlled Drug Delivery from Nanotherapeutics.Recent advances in drug delivery and formulation · 2022Article
- Review
- Nonlinear Elastic and Inelastic Properties of Cells.Journal of biomechanical engineering · 2020Review
- A Toolbox for Organelle Mechanobiology Research-Current Needs and Challenges.Micromachines · 2019Article
- Emergent spatiotemporal dynamics of the actomyosin network in the presence of chemical gradients.Integrative biology : quantitative biosciences from nano to macro · 2019Article
- Picosecond orientational dynamics of water in living cells.Nature communications · 2017Article
- Biomolecular environment, quantification, and intracellular interaction of multifunctional magnetic SERS nanoprobes.The Analyst · 2016Article
- QUANTIFYING THE MOTION OF MAGNETIC PARTICLES IN EXCISED TISSUE: EFFECT OF PARTICLE PROPERTIES AND APPLIED MAGNETIC FIELD.Journal of magnetism and magnetic materials · 2015Article
- Effects of zinc oxide nanoparticles on Kupffer cell phagosomal motility, bacterial clearance, and liver function.International journal of nanomedicine · 2015Article
- Turning erythrocytes into functional micromotors.ACS nano · 2014Article
- A method for time-resolved measurements of the mechanics of phagocytic cups.Journal of the Royal Society, Interface · 2013Article
- A silicone-based stretchable micropost array membrane for monitoring live-cell subcellular cytoskeletal response.Lab on a chip · 2012Article
- Diminished organelle motion in murine Kupffer cells during the erythrocytic stage of malaria.Journal of the Royal Society, Interface · 2011Article
- Combining laser microsurgery and finite element modeling to assess cell-level epithelial mechanics.Biophysical journal · 2009Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
2 authors at 1 institution in 1 country.
Funding
Abstract
Submicrometer magnetic particles, ingested by cells and monitored via the magnetic fields they generate, provide an alternative to optical microscopy for probing movement and viscosity of living cytoplasm, and can be used for cells both in vitro and in vivo. We present methods for preparing lung macrophages tagged with magnetic particles for magnetometric study. Interpretation of the data involves fitting experimental remanent-field decay curves to nonlinear mechanistic models of intracellular particle motion. The model parameters are sensitive to mobility and apparent cytoplasmic viscosity experienced by particle-containing organelles. We present results of parameter estimation for intracellular particle behavior both within control cells and after (a) variable magnetization duration, (b) incubation with cytochalasin D, and (c) particle twisting by external fields. Magnetometric analysis showed cytoplasmic elasticity, dose-dependent motion inhibition by cytochalasin D, and a shear-thinning apparent viscosity.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.