Evidence map›Paper›PMID 36764261›Full record

ArticleGeneral hospital psychiatry

Development and validation of a brief screener for posttraumatic stress disorder risk in emergency medical settings.

K Schultebraucks, J S Stevens, V Michopoulos, J Maples-Keller, J Lyu, R N Smith, B O Rothbaum, K J Ressler, I R Galatzer-Levy, A Powers

Open access · greenAbstract read
In one paragraph

Article in General hospital psychiatry. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
2.5field-weighted citation impact, top 12% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 8 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 5 institutions in 1 country.

K SchultebraucksDepartment of Psychiatry, NYU Grossman School of Medicine, New York, USA; Department of Population Health, NYU Grossman School of Medicine, New York, USA. Electronic address: ks3796@cumc.columbia.edu.
J S StevensDepartment of Psychiatry and Behavioral Sciences, Emory University School of Medicine, Atlanta, GA, USA; Center for Visual and Neurocognitive Rehabilitation, Atlanta Veterans' Affairs Health Care System, Atlanta, GA, USA.
V MichopoulosDepartment of Psychiatry and Behavioral Sciences, Emory University School of Medicine, Atlanta, GA, USA.
J Maples-KellerDepartment of Psychiatry and Behavioral Sciences, Emory University School of Medicine, Atlanta, GA, USA.
J LyuDepartment of Biostatistics, Columbia University, Mailman School of Public Health, New York, NY, USA.
R N SmithDepartment of Surgery, Emory University School of Medicine, Atlanta, GA, USA; Department of Behavioral, Social and Health Education Sciences, Emory University School of Public Health, Atlanta, GA, USA.
B O RothbaumDepartment of Psychiatry and Behavioral Sciences, Emory University School of Medicine, Atlanta, GA, USA.
K J ResslerDepartment of Psychiatry, Harvard Medical School, Boston, MA, USA; McLean Hospital, Belmont, MA, USA.
I R Galatzer-LevyDepartment of Psychiatry, NYU Grossman School of Medicine, New York, USA.
A PowersDepartment of Psychiatry and Behavioral Sciences, Emory University School of Medicine, Atlanta, GA, USA.
Emory University · USNew York University · USAtlanta VA Health Care System · USColumbia University · USHarvard University · US

Funding

Point-of-care prognostic modeling of PTSD risk after traumatic event exposure using digital biomarkers and clinical data from electronic health records in the emergency department setting (PREDICT)R01MH129856 · NIMH · NEW YORK UNIVERSITY SCHOOL OF MEDICINE · PI Katharina Schultebraucks · 2022 to 2026
$4.1M
Early Signs:digital phenotyping to identify digital biomarkers for predicting burnout and cognitive functioning in ED clinicians (Early Signs)R01HL156134 · NHLBI · NEW YORK UNIVERSITY SCHOOL OF MEDICINE · PI SCHULTEBRAUCKS, KATHARINA · 2021 to 2025
$3.6M
2 of 2 Prospective Determination of Psychobiological Risk Factors for PTSDR01MH094757 · NIMH · EMORY UNIVERSITY · PI RESSLER, KERRY J. · 2012 to 2016
$2.3M
Application of Cognitive, Emotional and Biological Dimensions - Resubmission - 1K01MH102415 · NIMH · NEW YORK UNIVERSITY SCHOOL OF MEDICINE · PI GALATZER-LEVY, ISAAC R · 2014 to 2017
$665k
Primary-Care Based Mindfulness Intervention for Chronically Traumatized IndividualsK23AT009713 · NCCIH · EMORY UNIVERSITY · PI LOTT, ABIGAIL POWERS · 2018 to 2021
$538k
NCCIH NIH HHS K23 AT009713NHLBI NIH HHS R01 HL156134NIMH NIH HHS K01 MH102415NIMH NIH HHS R01 MH094757NIMH NIH HHS R01 MH129856
6 · The paper itself

Abstract

objectivePredicting risk of posttraumatic stress disorder (PTSD) in the acute care setting is challenging given the pace and acute care demands in the emergency department (ED) and the infeasibility of using time-consuming assessments. Currently, no accurate brief screening for long-term PTSD risk is routinely used in the ED. One instrument widely used in the ED is the 27-item Immediate Stress Reaction Checklist (ISRC). The aim of this study was to develop a short screener using a machine learning approach and to investigate whether accurate PTSD prediction in the ED can be achieved with substantially fewer items than the IRSC.

methodThis prospective longitudinal cohort study examined the development and validation of a brief screening instrument in two independent samples, a model development sample (N = 253) and an external validation sample (N = 93). We used a feature selection algorithm to identify a minimal subset of features of the ISRC and tested this subset in a predictive model to investigate if we can accurately predict long-term PTSD outcomes.

resultsWe were able to identify a reduced subset of 5 highly predictive features of the ISRC in the model development sample (AUC = 0.80), and we were able to validate those findings in the external validation sample (AUC = 0.84) to discriminate non-remitting vs. resilient trajectories.

conclusionThis study developed and validated a brief 5-item screener in the ED setting, which may help to improve the diagnostic process of PTSD in the acute care setting and help ED clinicians plan follow-up care when patients are still in contact with the healthcare system. This could reduce the burden on patients and decrease the risk of chronic PTSD.

Indexed as

Stress Disorders, Post-TraumaticEmergency Service, HospitalHumansLongitudinal StudiesProspective StudiesAcute traumaEmergency departmentMachine learningPosttraumatic stress disorderScreener

Identifiers

PMID36764261
PMCPMC10866012
OpenAlexW4318317818

What OpenQuestion holds

Textmetadata
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.