Evidence map›Paper›PMID 36763922›Full record

ArticleJCO oncology practice2023

Fertility Preservation Practices at Pediatric Oncology Institutions in the United States: A Report From the Children's Oncology Group.

Natasha N Frederick, James L Klosky, Lillian Meacham, Gwendolyn P Quinn, Joanne F Kelvin, Brooke Cherven, David R Freyer, Christopher C Dvorak, Julienne Brackett, Sameeya Ahmed-Winston and 4 more

Registry-linked trialOpen access · greenAbstract read
In one paragraph

Article in JCO oncology practice, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT07658937 (Improving Sexual and Reproductive Health Communication Between Adolescent and Young Adult Oncology Patients and Clinicians), which is not on this map. Cited by 15 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
15citing papers in PubMed, 1 pooled it
7.8field-weighted citation impact, top 2% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT07658937 nanot yet recruitingnot on this mapstarted 2026, after this paper: background citation

Improving Sexual and Reproductive Health Communication Between Adolescent and Young Adult Oncology Patients and Clinicians: ReSPECT Intervention Proof-of-Concept Testing

TypeinterventionalSponsorConnecticut Children's Medical CenterRan2026 to 2029Enrolled30ConditionsHealth-Related Quality-of-Life, Cancer, Health CommunicationArmsReSPECT
3 · Its place in the literature

Who cites it

15 citing papers in PubMed, 1 synthesis or guideline pooled it, 27 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

14 authors at 12 institutions in 1 country.

Natasha N FrederickCenter for Cancer and Blood Disorders, Connecticut Children's Medical Center, Hartford, CT.
James L KloskyAflac Cancer and Blood Disorders Center at Children's Healthcare of Atlanta, Atlanta, GA.
Lillian MeachamAflac Cancer and Blood Disorders Center at Children's Healthcare of Atlanta, Atlanta, GA.
Gwendolyn P QuinnDivision of Medical Ethics, Departments of OB-GYN, Population Health, Grossman School of Medicine, New York University, New York, NY.ORCID 0000-0002-4208-9889
Joanne F KelvinMemorial Sloan Kettering Cancer Center, New York, NY.
Brooke ChervenAflac Cancer and Blood Disorders Center at Children's Healthcare of Atlanta, Atlanta, GA.
David R FreyerCancer and Blood Disease Institute, Children's Hospital, Los Angeles, CA.
Christopher C DvorakDivision of Pediatric Allergy, Immunology and Bone Marrow Transplant, University of California San Francisco, San Francisco, CA.ORCID 0000-0002-6146-3952
Julienne BrackettDepartment of Pediatrics, Baylor College of Medicine, Texas Children's Cancer and Hematology Centers, Houston, TX.ORCID 0000-0002-6782-1044
Sameeya Ahmed-WinstonCenter for Cancer and Blood Disorders, Children's National, Washington, DC.ORCID 0000-0002-4359-1520
Elyse BrysonAflac Cancer and Blood Disorders Center at Children's Healthcare of Atlanta, Atlanta, GA.
H Irene SuDivision of Reproductive Endocrinology and Infertility, Department of Obstetrics, Gynecology and Reproductive Sciences, University of California, San Diego, CA.ORCID 0000-0002-6671-5151
Eric J ChowClinical Research and Public Health Sciences Divisions, Fred Hutchinson Cancer Center, Seattle, WA.ORCID 0000-0001-7712-961X
Jennifer LevineDivision of Pediatric Hematology and Oncology, Weill Cornell Medicine, New York, NY.ORCID 0000-0003-1417-0169
Aflac (United States) · USBaylor College of Medicine · USCenter for Cancer and Blood Disorders · USConnecticut Children's Medical Center · USCornell University · USEmory University · USFred Hutch Cancer Center · USMemorial Sloan Kettering Cancer Center · USNew York University · USUniversity of California San Diego · USUniversity of California, San Francisco · USUniversity of Southern California · US

Funding

NCTN BIQSFP ANBL1531 (NRT)U10CA180886 · NCI · PUBLIC HEALTH INSTITUTE · PI Douglas S. Hawkins · 2014 to 2026
$390.6M
X-RAY CRYSTALLOGRAPHYP30CA008748 · NCI · SLOAN-KETTERING INSTITUTE FOR CANCER RES · PI SELWYN M VICKERS · 1985 to 2026
$347.4M
Translational Bioimaging Core Shared ResourceP30CA015704 · NCI · FRED HUTCHINSON CANCER RESEARCH CENTER · PI Eric Collisson · 1985 to 2026
$296.4M
Towards a preventive cancer vaccine for children with constitutional mismatch repair deficiencyUG1CA189955 · NCI · PUBLIC HEALTH INSTITUTE · PI BRAD H POLLOCK, Michael E. Roth · 2014 to 2026
$62.5M
NCI NIH HHS P30 CA008748NCI NIH HHS P30 CA015704NCI NIH HHS U10 CA180886NCI NIH HHS UG1 CA189955
6 · The paper itself

Abstract

purposeFertility discussions are an integral part of comprehensive care for pediatric, adolescent, and young adult patients newly diagnosed with cancer and are supported by national guidelines. Current institutional practices are poorly understood.

methodsA cross-sectional survey was distributed to 220 Children's Oncology Group member institutions regarding fertility discussion practices. Descriptive statistics were calculated for all variables. The association between specific practices and selected outcomes on the basis of sex was examined via multivariable logistic regression.

resultsOne hundred forty-four programs (65.5%) returned surveys. Of these, 65 (45.1%) reported routine discussions of fertility with all female patients and 55 (38.5%) all male patients (

conclusionDespite recommended guidelines, fertility discussions with patients/families before treatment initiation are not routine at Children's Oncology Group institutions. Standard criteria to determine which options should be offered to patients are more common for males than females.

Indexed as

Fertility PreservationNeoplasmsAdolescentChildCross-Sectional StudiesFemaleHumansMaleMedical OncologySemenUnited StatesYoung Adult

Identifiers

PMID36763922
PMCPMC10113112
OpenAlexW4319879860

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.