Evidence map›Paper›PMID 36763788›Full record

ArticleJournal of the American Chemical Society2023

Enantioselective Hydroalkoxylation of 1,3-Dienes via Ni-Catalysis.

Qi Li, Zhen Wang, Vy M Dong, Xiao-Hui Yang

Abstract read
In one paragraph

Article in Journal of the American Chemical Society, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed.

  1. Article
  2. Article
  3. Dual-Ligand Strategy in Rh-Catalyzed Sequential Hydrofunctionalization of Valylene.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2025
    Article
  4. Article
  5. Palladium-catalyzed remote internal C(spNature communications · 2024
    Article
  6. Dienes as Versatile Substrates for Transition Metal-Catalyzed Reactions.Angewandte Chemie (International ed. in English) · 2024
    Review
  7. Article
  8. Asymmetric formal spNature communications · 2023
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Qi LiAdvanced Research Institute of Multidisciplinary Science, School of Chemistry and Chemical Engineering, Key Laboratory of Medical Molecule Science and Pharmaceutical Engineering, Ministry of Industry and Information Technology, Beijing Institute of Technology, Beijing 100081, P. R. China.ORCID 0000-0002-5733-420X
Zhen WangAdvanced Research Institute of Multidisciplinary Science, School of Chemistry and Chemical Engineering, Key Laboratory of Medical Molecule Science and Pharmaceutical Engineering, Ministry of Industry and Information Technology, Beijing Institute of Technology, Beijing 100081, P. R. China.
Vy M DongDepartment of Chemistry, University of California-Irvine, Irvine, California 92697, United States.ORCID 0000-0002-8099-1048
Xiao-Hui YangAdvanced Research Institute of Multidisciplinary Science, School of Chemistry and Chemical Engineering, Key Laboratory of Medical Molecule Science and Pharmaceutical Engineering, Ministry of Industry and Information Technology, Beijing Institute of Technology, Beijing 100081, P. R. China.ORCID 0000-0001-6884-2587

Funding

Innovative Tools for Chemical Synthesis: Metal-Hydride Catalysis, Medicinal Motifs, and Molecular ProbesR35GM127071 · NIGMS · UNIVERSITY OF CALIFORNIA-IRVINE · PI Vy M Dong · 2018 to 2026
$4.9M
NIGMS NIH HHS R35 GM127071
6 · The paper itself

Abstract

As an advance in hydrofunctionalization, we herein report that alcohols add to 1,3-dienes with high regio- and enantioselectivity. Using Ni-DuPhos, we access enantioenriched allylic ethers. Through the choice of solvent-free conditions, we control the reversibility of C-O bond formation. This work showcases a rare example of methanol as a reagent in asymmetric synthesis.

Identifiers

PMID36763788
PMCPMC9951252

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.