Evidence map›Paper›PMID 36763494›Full record

ArticleACS sensors2023

Impedimetric Nanobiosensor for the Detection of SARS-CoV-2 Antigens and Antibodies.

Diana Isabel Sandoval Bojórquez, Željko Janićijević, Brenda Palestina Romero, Eduardo Sergio Oliveros Mata, Markus Laube, Anja Feldmann, Alexandra Kegler, Laura Drewitz, Ciarán Fowley, Jens Pietzsch and 4 more

Erratum issuedOpen access · hybridAbstract read
In one paragraph

Article in ACS sensors, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
5.5field-weighted citation impact, top 4% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 36 citations in OpenAlex.

  1. Article
  2. Review
  3. Review
  4. Review
  5. Article
  6. Review
  7. Advances in the Use of Conducting Polymers for Healthcare Monitoring.International journal of molecular sciences · 2024
    Review
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

14 authors at 3 institutions in 1 country.

Diana Isabel Sandoval BojórquezInstitute of Radiopharmaceutical Cancer Research, Helmholtz-Zentrum Dresden-Rossendorf e.V. (HZDR), 01328 Dresden, Germany.
Željko JanićijevićInstitute of Radiopharmaceutical Cancer Research, Helmholtz-Zentrum Dresden-Rossendorf e.V. (HZDR), 01328 Dresden, Germany.
Brenda Palestina RomeroInstitute of Radiopharmaceutical Cancer Research, Helmholtz-Zentrum Dresden-Rossendorf e.V. (HZDR), 01328 Dresden, Germany.ORCID 0000-0003-1504-798X
Eduardo Sergio Oliveros MataInstitute of Ion Beam Physics and Materials Research, Helmholtz-Zentrum Dresden-Rossendorf e.V. (HZDR), 01328 Dresden, Germany.ORCID 0000-0002-7277-7287
Markus LaubeInstitute of Radiopharmaceutical Cancer Research, Helmholtz-Zentrum Dresden-Rossendorf e.V. (HZDR), 01328 Dresden, Germany.ORCID 0000-0003-4916-3794
Anja FeldmannInstitute of Radiopharmaceutical Cancer Research, Helmholtz-Zentrum Dresden-Rossendorf e.V. (HZDR), 01328 Dresden, Germany.
Alexandra KeglerInstitute of Radiopharmaceutical Cancer Research, Helmholtz-Zentrum Dresden-Rossendorf e.V. (HZDR), 01328 Dresden, Germany.
Laura DrewitzInstitute of Radiopharmaceutical Cancer Research, Helmholtz-Zentrum Dresden-Rossendorf e.V. (HZDR), 01328 Dresden, Germany.
Ciarán FowleyInstitute of Ion Beam Physics and Materials Research, Helmholtz-Zentrum Dresden-Rossendorf e.V. (HZDR), 01328 Dresden, Germany.
Jens PietzschInstitute of Radiopharmaceutical Cancer Research, Helmholtz-Zentrum Dresden-Rossendorf e.V. (HZDR), 01328 Dresden, Germany.ORCID 0000-0002-1610-1493
Juergen FassbenderInstitute of Ion Beam Physics and Materials Research, Helmholtz-Zentrum Dresden-Rossendorf e.V. (HZDR), 01328 Dresden, Germany.
Torsten TonnTransfusion Medicine, Med. Faculty Carl-Gustav Carus, Technische Universität Dresden, 01307 Dresden, Germany.
Michael BachmannInstitute of Radiopharmaceutical Cancer Research, Helmholtz-Zentrum Dresden-Rossendorf e.V. (HZDR), 01328 Dresden, Germany.
Larysa BarabanInstitute of Radiopharmaceutical Cancer Research, Helmholtz-Zentrum Dresden-Rossendorf e.V. (HZDR), 01328 Dresden, Germany.ORCID 0000-0003-1010-2791
Helmholtz-Zentrum Dresden-Rossendorf · DEGerman Cancer Research Center · DEGerman Red Cross · DE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Detection of antigens and antibodies (Abs) is of great importance in determining the infection and immunity status of the population, as they are key parameters guiding the handling of pandemics. Current point-of-care (POC) devices are a convenient option for rapid screening; however, their sensitivity requires further improvement. We present an interdigitated gold nanowire-based impedance nanobiosensor to detect COVID-19-associated antigens (receptor-binding domain of S1 protein of the SARS-CoV-2 virus) and respective Abs appearing during and after infection. The electrochemical impedance spectroscopy technique was used to assess the changes in measured impedance resulting from the binding of respective analytes to the surface of the chip. After 20 min of incubation, the sensor devices demonstrate a high sensitivity of about 57 pS·s

Indexed as

COVID-19SARS-CoV-2Antibodies, ViralHumansLimit of DetectionPoint-of-Care SystemsAntibodies, Viralelectrochemical impedance spectroscopy (EIS)gold nanowiresimpedance modelimpedimetric sensingpoint-of-care testingreliabilitySARS-CoV-2surface plasmon resonance (SPR)

Identifiers

PMID36763494
PMCPMC9940615
OpenAlexW4319826368

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.