Evidence map›Paper›PMID 36763410›Full record

ArticleeLife2023

Expansion and loss of sperm nuclear basic protein genes in

Ching-Ho Chang, Isabel Mejia Natividad, Harmit S Malik

Open access · goldAbstract read
In one paragraph

Article in eLife, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 34 papers.

0numbers the graph read from it
0cells of the map it votes in
34citing papers in PubMed
12.5field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

34 citing papers in PubMed, 40 citations in OpenAlex.

  1. Article
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  6. Article
  7. The evolutionary genomics of meiotic drive.Molecular biology and evolution · 2026
    Article
  8. Article
  9. Article
  10. Article
  11. Rapid protamine evolution suppresses meiotic drive inbioRxiv : the preprint server for biology · 2025
    Article
  12. Article
  13. Article
  14. Article
  15. Article
  16. Article
  17. Article
  18. Review
  19. Article
  20. An orphan gene is essential for efficient sperm entry into eggs inbioRxiv : the preprint server for biology · 2024
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 1 institution in 2 countries.

Ching-Ho ChangDivision of Basic Sciences, Fred Hutchinson Cancer Center, Seattle, United States.ORCID 0000-0001-9361-1190
Isabel Mejia NatividadDivision of Basic Sciences, Fred Hutchinson Cancer Center, Seattle, United States.
Harmit S MalikDivision of Basic Sciences, Fred Hutchinson Cancer Center, Seattle, United States.ORCID 0000-0001-6005-0016
Cape Town HVTN Immunology Laboratory / Hutchinson Centre Research Institute of South Africa · ZA

Funding

Resource Project CoreU41HG000739 · NHGRI · HARVARD UNIVERSITY · PI PERRIMON, NORBERT · 2014 to 2022
$32.3M
Resource Component: Acquisition, maintenance and distribution of Drosophila stocksP40OD018537 · OD · TRUSTEES OF INDIANA UNIVERSITY · PI Annette L. Parks · 2014 to 2026
$13.5M
Genetic Conflict Shapes Centromeres and HeterochromatinR01GM074108 · NIGMS · FRED HUTCHINSON CANCER RESEARCH CENTER · PI MALIK, HARMIT S. · 2005 to 2022
$6.1M
Howard Hughes Medical InstituteNHGRI NIH HHS U41 HG000739NIGMS NIH HHS R01 GM074108NIH HHS P40 OD018537
6 · The paper itself

Abstract

Many animal species employ sperm nuclear basic proteins (SNBPs) or protamines to package sperm genomes tightly. SNBPs vary across animal lineages and evolve rapidly in mammals. We used a phylogenomic approach to investigate SNBP diversification in

Indexed as

DrosophilaDrosophila melanogasterAnimalsEvolution, MolecularMaleMammalsNuclear ProteinsSemenSex ChromosomesSpermatozoaSperm ProteinsNuclear Proteinssperm basic nuclear proteinsSperm ProteinsD. melanogasterevolutionary biologygeneticsgenomicsmeiotic drivepositive selectionprotaminespseudogenes

Identifiers

PMID36763410
PMCPMC9917458
OpenAlexW4319812955

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.