ArticleLa Radiologia medica2023
Clinical utility of abbreviated breast MRI based on diffusion tensor imaging in patients underwent breast conservative therapy.
Article in La Radiologia medica, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.
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4 citing papers in PubMed, 3 citations in OpenAlex.
- Abbreviated MRI Protocols in Breast Cancer Diagnosis: A Narrative Review.Journal of clinical medicine · 2026Review
- Diagnostic performance of kinetic parameters derived from ultrafast breast MRI in characterizing benign and malignant breast lesions: the added value of the semiautomatically based parameters.Insights into imaging · 2025Article
- AI-driven MRI biomarker for triple-class HER2 expression classification in breast cancer: a large-scale multicenter study.Breast cancer research : BCR · 2025Article
- Contrast Agents in Breast MRI: State of the Art and Future Perspectives.Biomedicines · 2025Review
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6 authors at 1 institution in 1 country.
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Abstract
purposeTo evaluate the added value of the diffusion tensor imaging (DTI) parameters to abbreviated breast MRI protocol in differentiating recurrent breast cancer from post-operative changes in cases of breast conservative surgery (BCS).
methodsThis prospective study was approved by our institutional review board. Written informed consent was obtained in all patients. 47 female patients (mean age, 49 years; range, 32-66 years) that previously underwent breast conservative surgery with a palpable mass were included in this study (62 breast lesions). Two abbreviated MRI protocols were compared using 1.5 Tesla MRI, AB-MRI 1 (axial T1, T2, pre-contrast T1, 1st post-contrast and subtracted images) and AB-MRI 2 (same sequences plus adding DTI). In both protocols, the wash-in rate was calculated. Histopathology was used as the standard of reference. Appropriate statistical tests were used to assess sensitivity, specificity, and diagnostic accuracy for each protocol.
resultsThe mean total acquisition time was of 6 min for AB-MRI 1 and 10 min for AB-MRI 2 protocols while the mean interpretation time was of 57.5 and 75 s, respectively. Among analyzed DTI parameters, MD (mean diffusivity) showed the highest sensitivity (96.43%) and specificity (91.18%) (P value = < 0.001). FA (fractional anisotropy), AD (axial diffusivity) and RD (radial diffusivity) showed sensitivity = (78.57%, 82.14% and 85.71%), specificity = (88.24, 85.29% and 79.41%), respectively, P value (< 0.001).
conclusionDTI may be included in abbreviated MRI protocols without a significant increase in acquisition time and with the advantage of increasing specificity and clinical utility in the characterization of post-conservative breast lesions.
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