Evidence map›Paper›PMID 36763255›Full record

ArticleSleep & breathing = Schlaf & Atmung2023

Impact of antiallergy agents on CPAP therapy and sleep quality with spring pollinosis in Japanese.

Akihisa Yoshikawa, Ayako Inoshita, Naoko Sata, Masahiro Nakamura, Yo Suzuki, Erina Ishimizu, Shoko Suda, Ryo Naito, Takatoshi Kasai, Fumihiko Matsumoto

Open access · bronzeAbstract read
In one paragraph

Article in Sleep & breathing = Schlaf & Atmung, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed, 1 pooled it
1.0field-weighted citation impact, top 25% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 1 synthesis or guideline pooled it, 4 citations in OpenAlex.

  1. Maximizing outcomes by multimodal treatment in obstructive sleep apnea: a systematic review and meta-analysis.European archives of oto-rhino-laryngology : official journal of the European Federation of Oto-Rhino-Laryngological Societies (EUFOS) : affiliated with the German Society for Oto-Rhino-Laryngology - Head and Neck Surgery · 2026
    Pooled it
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 1 institution in 1 country.

Akihisa YoshikawaDepartment of Otorhinolaryngology, Head and Neck Surgery, Juntendo University Graduate School of Medicine, 2-1-1 Hongo, Tokyo, Bunkyo-Ku, 113-8421, Japan.
Ayako InoshitaDepartment of Otorhinolaryngology, Head and Neck Surgery, Juntendo University Graduate School of Medicine, 2-1-1 Hongo, Tokyo, Bunkyo-Ku, 113-8421, Japan. ayaent@juntendo.ac.jp.ORCID 0000-0003-4401-3594
Naoko SataDepartment of Otorhinolaryngology, Head and Neck Surgery, Juntendo University Graduate School of Medicine, 2-1-1 Hongo, Tokyo, Bunkyo-Ku, 113-8421, Japan.
Masahiro NakamuraDepartment of Otorhinolaryngology, Head and Neck Surgery, Juntendo University Graduate School of Medicine, 2-1-1 Hongo, Tokyo, Bunkyo-Ku, 113-8421, Japan.
Yo SuzukiDepartment of Otorhinolaryngology, Head and Neck Surgery, Juntendo University Graduate School of Medicine, 2-1-1 Hongo, Tokyo, Bunkyo-Ku, 113-8421, Japan.
Erina IshimizuDepartment of Otorhinolaryngology, Head and Neck Surgery, Juntendo University Graduate School of Medicine, 2-1-1 Hongo, Tokyo, Bunkyo-Ku, 113-8421, Japan.
Shoko SudaSleep and Sleep-Disordered Breathing Center, Juntendo University Hospital, Tokyo, Japan.
Ryo NaitoSleep and Sleep-Disordered Breathing Center, Juntendo University Hospital, Tokyo, Japan.
Takatoshi KasaiSleep and Sleep-Disordered Breathing Center, Juntendo University Hospital, Tokyo, Japan.
Fumihiko MatsumotoDepartment of Otorhinolaryngology, Head and Neck Surgery, Juntendo University Graduate School of Medicine, 2-1-1 Hongo, Tokyo, Bunkyo-Ku, 113-8421, Japan.
Juntendo University · JP

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposeAllergic rhinitis (AR) is associated with obstructive sleep apnea (OSA) and nasal obstruction causes decreased adherence to continuous positive airway pressure (CPAP). The purpose is to evaluate the effects of antiallergic agents on CPAP adherence and sleep quality.

methodsA longitudinal study was made of patients who use CPAP for OSA and treated with antiallergy agents for spring pollinosis. We compared the Pittsburgh Sleep Quality Index (PSQI), Epworth Sleepiness Scale (ESS), nasal symptoms scores (NSS), and data from CPAP before and after treatment. Then, we classified the subjects into two groups based on the baseline PSQI score: one group without a decreased sleep quality (PSQI < 6) and the other group with decreased sleep quality (PSQI ≥ 6).

resultsOf 28 subjects enrolled, 13 had good sleep quality and 15 had poor sleep quality. PSQI showed significant improvements after medication (p = 0.046). ESS showed no significant differences after AR medication (p = 0.565). Significant improvement was observed after the prescription of antiallergy agents in all items of NSS (sneezing, p < 0.05; rhinorrhea, p < 0.01; nasal obstruction, p < 0.01; QOL, p < 0.01). The percentage of days with CPAP use more than 4 h increased significantly after the administration of rhinitis medication (p = 0.022). In the intragroup comparisons of PSQI ≥ 6 group, PSQI decreased significantly (p < 0.05). For the NSS in intragroup comparisons of PSQI ≥ 6 group, all parameters showed significant improvement (sneezing, p = 0.016; rhinorrhea, p = 0.005; nasal obstruction, p < 0.005; QOL, p < 0.005).

conclusionThe use of antiallergy agents can improve CPAP adherence and sleep quality in patients with OSA on CPAP.

Indexed as

Anti-Allergic AgentsNasal ObstructionRhinitis, Allergic, SeasonalSleep Apnea, ObstructiveContinuous Positive Airway PressureEast Asian PeopleHumansLongitudinal StudiesPatient ComplianceQuality of LifeRhinorrheaSleep QualitySneezingAnti-Allergic AgentsAllergic rhinitisAntiallergic agentsCPAP adherenceObstructive sleep apneaSleep quality

Identifiers

PMID36763255
PMCPMC9911947
OpenAlexW4319827397

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.