Evidence map›Paper›PMID 36763245›Full record

ArticleAging clinical and experimental research2023

Efficacy and safety profile of GreenLight laser photoselective vaporization of the prostate in ≥ 75 years old patients: results from the Italian GreenLight Laser Study Group.

Davide Campobasso, Simone Morselli, Francesco Greco, Cosimo De Nunzio, Paolo Destefanis, Giuseppe Fasolis, Francesco Varvello, Salvatore Voce, Giulio Reale, Tommaso Cai and 17 more

Open access · greenAbstract readMulticenter Study
PubMed Publisher
In one paragraph

Article in Aging clinical and experimental research, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed, 1 pooled it
2.4field-weighted citation impact, top 13% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 1 synthesis or guideline pooled it, 8 citations in OpenAlex.

  1. Pooled it
  2. Article
  3. Article
  4. Article
  5. Review
  6. Article
  7. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

27 authors at 18 institutions in 1 country.

Davide CampobassoUrology Unit, Civil Hospital of Guastalla, Azienda USL-IRCCS di Reggio Emilia, Via Donatori di Sangue 1, 42016, Guastalla, RE, Italy. d.campobasso@virgilio.it.ORCID http://orcid.org/0000-0003-2072-114X
Simone MorselliDepartment of Urology, "Hesperia Hospital", Centro Urologico Europeo (C.Ur.E), Modena, Italy.
Francesco GrecoUrologic Clinic, Centro Salute Uomo, Bergamo, Italy.
Cosimo De NunzioDepartment of Urology, "Sant'Andrea" Hospital, Sapienza University, Rome, Italy.
Paolo DestefanisDepartment of Urology, Azienda Ospedaliera Città della Salute e della Scienza di Turin-Sede Molinette, Turin, Italy.
Giuseppe FasolisDepartment of Urology, "S. Lazzaro" Hospital, Alba, Italy.
Francesco VarvelloDepartment of Urology, "S. Lazzaro" Hospital, Alba, Italy.
Salvatore VoceDepartment of Urology, Santa Maria delle Croci Hospital", Ravenna, Italy.
Giulio RealeDepartment of Urology, Santa Maria delle Croci Hospital", Ravenna, Italy.
Tommaso CaiDepartment of Urology, Santa Chiara Regional Hospital, Trento, Italy.
Rino OritiDepartment of Urology, "Ulivella e Glicini Clinic", Florence, Italy.
Agostino TuccioDepartment of Urology, University of Florence, Unit of Oncologic Minimally-Invasive Urology and Andrology, Careggi Hospital, Florence, Italy.
Lorenzo RuggeraDepartment of Urology, Clinica Urologica Azienda Ospedaliera - University of Padova, Padua, Italy.
Antonino LaganàDepartment of Urology, "S. Giovanni Evangelista" Hospital, Tivoli, Italy.
Claudio DadoneDepartment of Urology, Santa Croce e Carle" Hospital, Cuneo, Italy.
Paolo GonteroDepartment of Urology, Azienda Ospedaliera Città della Salute e della Scienza di Turin-Sede Molinette, Turin, Italy.
Gaetano De RienzoDepartment of Emergency and Organ Transplantation, Urology and Andrology Unit II, University of Bari, Bari, Italy.
Luigi PucciDepartment of Urology, AORN "Antonio Cardarelli", Naples, Italy.
Maurizio CarrinoDepartment of Urology, AORN "Antonio Cardarelli", Naples, Italy.
Franco MontefioreDepartment of Urology, San Giacomo" Hospital, Novi Ligure, Italy.
Salvatore RabitoDepartment of Urology, "Hesperia Hospital", Centro Urologico Europeo (C.Ur.E), Modena, Italy.
Roberto MianoUOSD Urologia, Fondazione Policlinico Tor Vergata, Rome, Italy.
Luigi SchipsDepartment of Medical, Oral and Biotechnological Sciences, "G. D'Annunzio" University of Chieti, Chieti, Italy.
Antonio FrattiniUrology Unit, Civil Hospital of Guastalla, Azienda USL-IRCCS di Reggio Emilia, Via Donatori di Sangue 1, 42016, Guastalla, RE, Italy.
Salvatore MicaliDepartment of Urology, University of Modena and Reggio Emilia, Modena, Italy.
Giovanni FerrariDepartment of Urology, "Hesperia Hospital", Centro Urologico Europeo (C.Ur.E), Modena, Italy.
Luca CindoloDepartment of Urology, "Hesperia Hospital", Centro Urologico Europeo (C.Ur.E), Modena, Italy.
Hesperia Hospital · ITAzienda Ospedaliera Citta' della Salute e della Scienza di Torino · ITAzienda Sanitaria Locale CN2 · ITOspedale Antonio Cardarelli · ITOspedale "Santa Maria delle Croci" di Ravenna · ITAzienda Ospedale - Università Padova · ITAzienda Ospedaliera Sant'Andrea · ITAzienda Ospedaliero-Universitaria Careggi · ITAzienda Sanitaria Ospedaliera S.Croce e Carle Cuneo · ITIstituti di Ricovero e Cura a Carattere Scientifico · ITOspedale Maggiore · ITOspedale San Giacomo Apostolo · ITOspedale Santa Chiara · ITPoliclinico Tor Vergata · ITUniversity of Bari Aldo Moro · ITUniversity of Chieti-Pescara · ITUniversity of Modena and Reggio Emilia · ITUniversity of Parma · IT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundBenign Prostatic Obstruction (BPO) is the most common non-malignant urological condition among men and its incidence rise with age. Among prostate treatments, GreenLight laser seems to reduce bleeding and would be safer in the aging population.

aimsWe aimed to compare the functional outcomes and safety profile of < 75 years old (Group A) and ≥ 75 years old (Group B) patients.

methodsIn a multicenter setting, we retrospectively analyzed all the patients treated with GreenLight Laser vaporization of the prostate (PVP).

results1077 patients were eligible for this study. 757 belonged to Group A (median age 66 years) and 320 to Group B (median age 78 years). No differences were present between the two groups in terms of prostate volume, operative time, hospital stay, PSA decrease over time after surgery, complications and re-intervention rate with a median follow-up period of 18 months (IQR 12-26). Nevertheless, focusing on complications, GreenLight laser PVP demonstrated an excellent safety profile in terms of hospital stay, re-intervention and complications, with an overall 29.6% complication rate in older patients and only two cases of Clavien III. Functional outcomes were similar at 12 month and became in favor of Group A over time. These data are satisfactory with a Qmax improvement of 111.7% and an IPSS reduction of 69.5% in older patients. DISCUSSION AND

conclusionsGreenLight laser photoselective vaporization of the prostate is a safe and efficient procedure for all patients, despite their age, with comparable outcomes and an equal safety profile.

Indexed as

Laser TherapyProstatic HyperplasiaAgedHumansLasersMaleProstateRetrospective StudiesTreatment OutcomeVolatilizationComplicationsElderlyGreenLight laserOutcomesPhotoselective vaporization of the prostate

Identifiers

PMID36763245
OpenAlexW4319812530

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.