Evidence map›Paper›PMID 36763225›Full record

ArticleClinical rheumatology2023

Analysis of microRNA-199a-3p expression in CD4

Huijing Wang, Guannan Geng, Danting Zhang, Fei Han, Shuang Ye

Abstract read
PubMed Publisher
In one paragraph

Article in Clinical rheumatology, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
0.7field-weighted citation impact, top 29% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 3 citations in OpenAlex.

  1. Review
  2. Review
  3. Review
  4. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 2 institutions in 1 country.

Huijing Wang *Department of Rheumatology, Renji Hospital, Shanghai Jiaotong University School of Medicine, Shanghai, China.
Guannan Geng *Department of Rheumatology, Renji Hospital, Shanghai Jiaotong University School of Medicine, Shanghai, China.
Danting ZhangDepartment of Rheumatology, Renji Hospital, Shanghai Jiaotong University School of Medicine, Shanghai, China.
Fei HanKidney Disease Center, The First Affiliated Hospital, Zhejiang University School of Medicine, Institute of Nephrology, Zhejiang University, Key Laboratory of Kidney Disease Prevention and Control Technology, Hangzhou, China.
Shuang YeDepartment of Rheumatology, Renji Hospital, Shanghai Jiaotong University School of Medicine, Shanghai, China. ye_shuang2000@163.com.ORCID http://orcid.org/0000-0002-5257-5768
Renji Hospital · CNFirst Affiliated Hospital Zhejiang University · CN

Funding

Clinical Research Plan of SHDC SHDC2020CR1015BCultivating Funds of Renji Hospital South Campus 2016PWGZR05
6 · The paper itself

Abstract

objectivesAccumulating evidence have suggested microRNAs (miRNAs) play important roles in the pathogenesis of systemic lupus erythematosus (SLE). Here we aimed to explore aberrant expression of miRNAs in CD4

methodsFirst, next-generation sequencing was performed on CD4

resultsA total of 66 upregulated miRNAs and 70 downregulated miRNAs were found between SLE and normal CD4

conclusionOur study suggested a novel and promising role of miR-199a-3p in CD4

Indexed as

Arthritis, RheumatoidLupus Erythematosus, SystemicMicroRNAsCD4-Positive T-LymphocytesHumansUp-RegulationMicroRNAsBiomarkerCD4+ T cellsJAK-STAT signaling pathwaymicroRNASystemic lupus erythematosus

Identifiers

PMID36763225
OpenAlexW4319812714

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.